000			02210 a2200577 4500
005			20250515093231.0
264		0	_c20080522
008			200805s 0 0 eng d
022			_a0145-2126
024	7		_a10.1016/j.leukres.2007.09.017 _2doi
040			_aNLM _beng _cNLM
100	1		_aNishioka, Chie
245	0	0	_aBlockade of MEK/ERK signaling enhances sunitinib-induced growth inhibition and apoptosis of leukemia cells possessing activating mutations of the FLT3 gene. _h[electronic resource]
260			_bLeukemia research _cJun 2008
300			_a865-72 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAged
650	0	4	_aAged, 80 and over
650	0	4	_aAntineoplastic Combined Chemotherapy Protocols
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aBenzimidazoles _xtherapeutic use
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aIndoles _xtherapeutic use
650	0	4	_aLeukemia _xdrug therapy
650	0	4	_aLeukemia, Megakaryoblastic, Acute _xdrug therapy
650	0	4	_aLeukemia, Myeloid, Acute _xdrug therapy
650	0	4	_aMAP Kinase Kinase 1 _xantagonists & inhibitors
650	0	4	_aMale
650	0	4	_aMiddle Aged
650	0	4	_aMitogen-Activated Protein Kinase 1 _xantagonists & inhibitors
650	0	4	_aMitogen-Activated Protein Kinase 3 _xantagonists & inhibitors
650	0	4	_aMutation _xgenetics
650	0	4	_aPyrroles _xtherapeutic use
650	0	4	_aRibosomal Protein S6 Kinases, 70-kDa _xantagonists & inhibitors
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aSunitinib
650	0	4	_aTumor Cells, Cultured
650	0	4	_afms-Like Tyrosine Kinase 3 _xgenetics
700	1		_aIkezoe, Takayuki
700	1		_aYang, Jing
700	1		_aTakeshita, Ayako
700	1		_aTaniguchi, Ayuko
700	1		_aKomatsu, Naoki
700	1		_aTogitani, Kazuto
700	1		_aKoeffler, H Phillip
700	1		_aYokoyama, Akihito
773	0		_tLeukemia research _gvol. 32 _gno. 6 _gp. 865-72
856	4	0	_uhttps://doi.org/10.1016/j.leukres.2007.09.017 _zAvailable from publisher's website
999			_c17501663 _d17501663