000 01791 a2200505 4500
005 20250515092953.0
264 0 _c20071123
008 200711s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.1146317
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMenuz, Karen
245 0 0 _aTARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_cNov 2007
300 _a815-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _a6-Cyano-7-nitroquinoxaline-2,3-dione
_xchemistry
650 0 4 _aAnimals
650 0 4 _aBenzodiazepines
_xpharmacology
650 0 4 _aBinding, Competitive
650 0 4 _aCell Line
650 0 4 _aCerebellum
_xcytology
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDrug Partial Agonism
650 0 4 _aHippocampus
_xcytology
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aInterneurons
_xdrug effects
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aPatch-Clamp Techniques
650 0 4 _aProtein Conformation
650 0 4 _aProtein Subunits
_xphysiology
650 0 4 _aPyramidal Cells
_xdrug effects
650 0 4 _aQuinoxalines
_xpharmacology
650 0 4 _aReceptors, AMPA
_xagonists
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSynaptic Transmission
_xdrug effects
650 0 4 _aTrichlormethiazide
_xpharmacology
700 1 _aStroud, Robert M
700 1 _aNicoll, Roger A
700 1 _aHays, Franklin A
773 0 _tScience (New York, N.Y.)
_gvol. 318
_gno. 5851
_gp. 815-7
856 4 0 _uhttps://doi.org/10.1126/science.1146317
_zAvailable from publisher's website
999 _c17493436
_d17493436