000 01788 a2200469 4500
005 20250515092425.0
264 0 _c20080408
008 200804s 0 0 eng d
022 _a1478-6362
024 7 _a10.1186/ar2315
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKrzeski, Piotr
245 0 0 _aDevelopment of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study.
_h[electronic resource]
260 _bArthritis research & therapy
_c2007
300 _aR109 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aDouble-Blind Method
650 0 4 _aFemale
650 0 4 _aFollow-Up Studies
650 0 4 _aHumans
650 0 4 _aHydroxamic Acids
_xadministration & dosage
650 0 4 _aMale
650 0 4 _aMatrix Metalloproteinase Inhibitors
650 0 4 _aMatrix Metalloproteinases
_xmetabolism
650 0 4 _aMiddle Aged
650 0 4 _aMusculoskeletal Diseases
_xchemically induced
650 0 4 _aOsteoarthritis, Knee
_xdrug therapy
650 0 4 _aProtease Inhibitors
_xadministration & dosage
700 1 _aBuckland-Wright, Chris
700 1 _aBálint, Géza
700 1 _aCline, Gary A
700 1 _aStoner, Karen
700 1 _aLyon, Robert
700 1 _aBeary, John
700 1 _aAronstein, William S
700 1 _aSpector, Tim D
773 0 _tArthritis research & therapy
_gvol. 9
_gno. 5
_gp. R109
856 4 0 _uhttps://doi.org/10.1186/ar2315
_zAvailable from publisher's website
999 _c17478379
_d17478379