000 02201 a2200685 4500
005 20250515092116.0
264 0 _c20080108
008 200801s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm070521y
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCole, Derek C
245 0 0 _aDiscovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cNov 2007
300 _a5535-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aBiological Availability
650 0 4 _aCHO Cells
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aDogs
650 0 4 _aFrontal Lobe
_xmetabolism
650 0 4 _aHaplorhini
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aMice
650 0 4 _aMicrodialysis
650 0 4 _aMicrosomes, Liver
_xmetabolism
650 0 4 _aRadioligand Assay
650 0 4 _aRats
650 0 4 _aReceptors, Serotonin
_xmetabolism
650 0 4 _aSerotonin Receptor Agonists
_xchemical synthesis
650 0 4 _aSolubility
650 0 4 _aStructure-Activity Relationship
650 0 4 _aThiazoles
_xchemistry
650 0 4 _aTryptamines
_xchemical synthesis
650 0 4 _agamma-Aminobutyric Acid
_xmetabolism
700 1 _aStock, Joseph R
700 1 _aLennox, William J
700 1 _aBernotas, Ronald C
700 1 _aEllingboe, John W
700 1 _aBoikess, Steve
700 1 _aCoupet, Joseph
700 1 _aSmith, Deborah L
700 1 _aLeung, Louis
700 1 _aZhang, Guo-Ming
700 1 _aFeng, Xidong
700 1 _aKelly, Michael F
700 1 _aGalante, Rocco
700 1 _aHuang, Pingzhong
700 1 _aDawson, Lee A
700 1 _aMarquis, Karen
700 1 _aRosenzweig-Lipson, Sharon
700 1 _aBeyer, Chad E
700 1 _aSchechter, Lee E
773 0 _tJournal of medicinal chemistry
_gvol. 50
_gno. 23
_gp. 5535-8
856 4 0 _uhttps://doi.org/10.1021/jm070521y
_zAvailable from publisher's website
999 _c17468925
_d17468925