000 | 02201 a2200685 4500 | ||
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005 | 20250515092116.0 | ||
264 | 0 | _c20080108 | |
008 | 200801s 0 0 eng d | ||
022 | _a0022-2623 | ||
024 | 7 |
_a10.1021/jm070521y _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aCole, Derek C | |
245 | 0 | 0 |
_aDiscovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist. _h[electronic resource] |
260 |
_bJournal of medicinal chemistry _cNov 2007 |
||
300 |
_a5535-8 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
650 | 0 | 4 | _aAdministration, Oral |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 | _aBiological Availability |
650 | 0 | 4 | _aCHO Cells |
650 | 0 | 4 | _aCricetinae |
650 | 0 | 4 | _aCricetulus |
650 | 0 | 4 | _aDogs |
650 | 0 | 4 |
_aFrontal Lobe _xmetabolism |
650 | 0 | 4 | _aHaplorhini |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aIn Vitro Techniques |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMicrodialysis |
650 | 0 | 4 |
_aMicrosomes, Liver _xmetabolism |
650 | 0 | 4 | _aRadioligand Assay |
650 | 0 | 4 | _aRats |
650 | 0 | 4 |
_aReceptors, Serotonin _xmetabolism |
650 | 0 | 4 |
_aSerotonin Receptor Agonists _xchemical synthesis |
650 | 0 | 4 | _aSolubility |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 |
_aThiazoles _xchemistry |
650 | 0 | 4 |
_aTryptamines _xchemical synthesis |
650 | 0 | 4 |
_agamma-Aminobutyric Acid _xmetabolism |
700 | 1 | _aStock, Joseph R | |
700 | 1 | _aLennox, William J | |
700 | 1 | _aBernotas, Ronald C | |
700 | 1 | _aEllingboe, John W | |
700 | 1 | _aBoikess, Steve | |
700 | 1 | _aCoupet, Joseph | |
700 | 1 | _aSmith, Deborah L | |
700 | 1 | _aLeung, Louis | |
700 | 1 | _aZhang, Guo-Ming | |
700 | 1 | _aFeng, Xidong | |
700 | 1 | _aKelly, Michael F | |
700 | 1 | _aGalante, Rocco | |
700 | 1 | _aHuang, Pingzhong | |
700 | 1 | _aDawson, Lee A | |
700 | 1 | _aMarquis, Karen | |
700 | 1 | _aRosenzweig-Lipson, Sharon | |
700 | 1 | _aBeyer, Chad E | |
700 | 1 | _aSchechter, Lee E | |
773 | 0 |
_tJournal of medicinal chemistry _gvol. 50 _gno. 23 _gp. 5535-8 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm070521y _zAvailable from publisher's website |
999 |
_c17468925 _d17468925 |