| 000 | 02200 a2200613 4500 | ||
|---|---|---|---|
| 005 | 20250515091822.0 | ||
| 264 | 0 | _c20071127 | |
| 008 | 200711s 0 0 eng d | ||
| 022 | _a0027-8424 | ||
| 024 | 7 |
_a10.1073/pnas.0708285104 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aDiFiglia, M | |
| 245 | 0 | 0 |
_aTherapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. _h[electronic resource] |
| 260 |
_bProceedings of the National Academy of Sciences of the United States of America _cOct 2007 |
||
| 300 |
_a17204-9 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aBehavior, Animal _xdrug effects |
| 650 | 0 | 4 |
_aCerebral Cortex _xdrug effects |
| 650 | 0 | 4 |
_aCholesterol _xmetabolism |
| 650 | 0 | 4 | _aDependovirus |
| 650 | 0 | 4 | _aDisease Models, Animal |
| 650 | 0 | 4 | _aGene Silencing |
| 650 | 0 | 4 | _aGenetic Therapy |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aHuntingtin Protein |
| 650 | 0 | 4 |
_aHuntington Disease _xpathology |
| 650 | 0 | 4 | _aInjections |
| 650 | 0 | 4 |
_aIntranuclear Inclusion Bodies _xdrug effects |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 |
_aMotor Neuron Disease _xpathology |
| 650 | 0 | 4 |
_aMutant Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aNeostriatum _xdrug effects |
| 650 | 0 | 4 |
_aNerve Tissue Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aNeurons _xpathology |
| 650 | 0 | 4 |
_aNeuropil Threads _xdrug effects |
| 650 | 0 | 4 |
_aNuclear Proteins _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aRNA, Small Interfering _xpharmacology |
| 700 | 1 | _aSena-Esteves, M | |
| 700 | 1 | _aChase, K | |
| 700 | 1 | _aSapp, E | |
| 700 | 1 | _aPfister, E | |
| 700 | 1 | _aSass, M | |
| 700 | 1 | _aYoder, J | |
| 700 | 1 | _aReeves, P | |
| 700 | 1 | _aPandey, R K | |
| 700 | 1 | _aRajeev, K G | |
| 700 | 1 | _aManoharan, M | |
| 700 | 1 | _aSah, D W Y | |
| 700 | 1 | _aZamore, P D | |
| 700 | 1 | _aAronin, N | |
| 773 | 0 |
_tProceedings of the National Academy of Sciences of the United States of America _gvol. 104 _gno. 43 _gp. 17204-9 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1073/pnas.0708285104 _zAvailable from publisher's website |
| 999 |
_c17460333 _d17460333 |
||