000 01773 a2200541 4500
005 20250515091441.0
264 0 _c20080108
008 200801s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm070902b
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aXia, Mingde
245 0 0 _aSynthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cNov 2007
300 _a5561-3 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aAnti-Inflammatory Agents, Non-Steroidal
_xchemical synthesis
650 0 4 _aArthritis, Experimental
_xdrug therapy
650 0 4 _aAsthma
_xdrug therapy
650 0 4 _aCell Line
650 0 4 _aChemotaxis
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aPiperidines
_xchemical synthesis
650 0 4 _aRats
650 0 4 _aRats, Inbred Lew
650 0 4 _aReceptors, CCR2
_xantagonists & inhibitors
650 0 4 _aStereoisomerism
650 0 4 _aStructure-Activity Relationship
700 1 _aHou, Cuifen
700 1 _aDeMong, Duane E
700 1 _aPollack, Scott R
700 1 _aPan, Meng
700 1 _aBrackley, James A
700 1 _aJain, Nareshkumar
700 1 _aGerchak, Chrissy
700 1 _aSinger, Monica
700 1 _aMalaviya, Ravi
700 1 _aMatheis, Michele
700 1 _aOlini, Gil
700 1 _aCavender, Druie
700 1 _aWachter, Michael
773 0 _tJournal of medicinal chemistry
_gvol. 50
_gno. 23
_gp. 5561-3
856 4 0 _uhttps://doi.org/10.1021/jm070902b
_zAvailable from publisher's website
999 _c17450623
_d17450623