000 02242 a2200673 4500
005 20250515073512.0
264 0 _c20071015
008 200710s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm070131b
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLiu, Ping
245 0 0 _aDiscovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[18F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cJul 2007
300 _a3427-30 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmides
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aBrain
_xdiagnostic imaging
650 0 4 _aCHO Cells
650 0 4 _aCricetinae
650 0 4 _aCricetulus
650 0 4 _aFluorine Radioisotopes
650 0 4 _aHumans
650 0 4 _aMacaca mulatta
650 0 4 _aPositron-Emission Tomography
650 0 4 _aPyridines
_xchemical synthesis
650 0 4 _aRadioligand Assay
650 0 4 _aRadiopharmaceuticals
_xchemical synthesis
650 0 4 _aReceptor, Cannabinoid, CB1
_xagonists
650 0 4 _aRecombinant Proteins
_xmetabolism
650 0 4 _aStructure-Activity Relationship
700 1 _aLin, Linus S
700 1 _aHamill, Terence G
700 1 _aJewell, James P
700 1 _aLanza, Thomas J
700 1 _aGibson, Raymond E
700 1 _aKrause, Stephen M
700 1 _aRyan, Christine
700 1 _aEng, Waisi
700 1 _aSanabria, Sandra
700 1 _aTong, Xinchun
700 1 _aWang, Junying
700 1 _aLevorse, Dorothy A
700 1 _aOwens, Karen A
700 1 _aFong, Tung M
700 1 _aShen, Chun-Pyn
700 1 _aLao, Julie
700 1 _aKumar, Sanjeev
700 1 _aYin, Wenji
700 1 _aPayack, Joseph F
700 1 _aSpringfield, Shawn A
700 1 _aHargreaves, Richard
700 1 _aBurns, H Donald
700 1 _aGoulet, Mark T
700 1 _aHagmann, William K
773 0 _tJournal of medicinal chemistry
_gvol. 50
_gno. 15
_gp. 3427-30
856 4 0 _uhttps://doi.org/10.1021/jm070131b
_zAvailable from publisher's website
999 _c17144482
_d17144482