000 01561 a2200397 4500
005 20250515072351.0
264 0 _c20070921
008 200709s 0 0 eng d
022 _a0006-2952
024 7 _a10.1016/j.bcp.2007.05.010
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPeters, Frank T
245 0 0 _aBiotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4'-hydroxymethyl-alpha-pyrrolidinobutyrophenone.
_h[electronic resource]
260 _bBiochemical pharmacology
_cAug 2007
300 _a511-20 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aBiotechnology
650 0 4 _aButyrophenones
_xmetabolism
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aCytochrome P-450 CYP2D6
_xgenetics
650 0 4 _aGas Chromatography-Mass Spectrometry
650 0 4 _aHumans
650 0 4 _aMagnetic Resonance Spectroscopy
650 0 4 _aPyrrolidines
_xmetabolism
650 0 4 _aRecombinant Proteins
_xgenetics
650 0 4 _aSchizosaccharomyces
_xgenetics
650 0 4 _aSpectrophotometry, Ultraviolet
700 1 _aDragan, Calin-A
700 1 _aWilde, Désirée R
700 1 _aMeyer, Markus R
700 1 _aZapp, Josef
700 1 _aBureik, Matthias
700 1 _aMaurer, Hans H
773 0 _tBiochemical pharmacology
_gvol. 74
_gno. 3
_gp. 511-20
856 4 0 _uhttps://doi.org/10.1016/j.bcp.2007.05.010
_zAvailable from publisher's website
999 _c17110307
_d17110307