000 02412 a2200673 4500
005 20250515065940.0
264 0 _c20071030
008 200710s 0 0 eng d
022 _a0006-4971
024 7 _a10.1182/blood-2007-02-073700
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYang, Jing
245 0 0 _aAZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo.
_h[electronic resource]
260 _bBlood
_cSep 2007
300 _a2034-40 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntibiotics, Antineoplastic
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aAurora Kinase A
650 0 4 _aAurora Kinase B
650 0 4 _aAurora Kinases
650 0 4 _aCase-Control Studies
650 0 4 _aCell Cycle
_xdrug effects
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aColony-Forming Units Assay
650 0 4 _aDaunorubicin
_xpharmacology
650 0 4 _aDrug Synergism
650 0 4 _aDrug Therapy, Combination
650 0 4 _aDrug Tolerance
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFemale
650 0 4 _aFlow Cytometry
650 0 4 _aHumans
650 0 4 _aImmunoblotting
650 0 4 _aLeukemia
_xdrug therapy
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aOrganophosphates
_xpharmacology
650 0 4 _aProtein Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aQuinazolines
_xpharmacology
650 0 4 _aThymidine
_xmetabolism
650 0 4 _aTransplantation, Heterologous
650 0 4 _aTubulin Modulators
_xpharmacology
650 0 4 _aVincristine
_xpharmacology
700 1 _aIkezoe, Takayuki
700 1 _aNishioka, Chie
700 1 _aTasaka, Taizo
700 1 _aTaniguchi, Ayuko
700 1 _aKuwayama, Yoshio
700 1 _aKomatsu, Naoki
700 1 _aBandobashi, Kentaro
700 1 _aTogitani, Kazuto
700 1 _aKoeffler, H Phillip
700 1 _aTaguchi, Hirokuni
700 1 _aYokoyama, Akihito
773 0 _tBlood
_gvol. 110
_gno. 6
_gp. 2034-40
856 4 0 _uhttps://doi.org/10.1182/blood-2007-02-073700
_zAvailable from publisher's website
999 _c17040411
_d17040411