000 01926 a2200589 4500
005 20250515065251.0
264 0 _c20070627
008 200706s 0 0 eng d
022 _a0918-6158
024 7 _a10.1248/bpb.30.1021
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aVenkatesh, Pilla Reddy
245 0 0 _aIn vitro phase I cytochrome P450 metabolism, permeability and pharmacokinetics of SB639, a novel histone deacetylase inhibitor in preclinical species.
_h[electronic resource]
260 _bBiological & pharmaceutical bulletin
_cMay 2007
300 _a1021-4 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAdministration, Oral
650 0 4 _aAnimals
650 0 4 _aBenzimidazoles
_xblood
650 0 4 _aBiological Availability
650 0 4 _aCaco-2 Cells
650 0 4 _aCell Membrane Permeability
_xdrug effects
650 0 4 _aCytochrome P-450 Enzyme System
_xmetabolism
650 0 4 _aDogs
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aEnzyme Inhibitors
_xblood
650 0 4 _aFemale
650 0 4 _aHalf-Life
650 0 4 _aHistone Deacetylase Inhibitors
650 0 4 _aHumans
650 0 4 _aHydroxamic Acids
_xblood
650 0 4 _aMale
650 0 4 _aMetabolic Detoxication, Phase I
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMicrosomes, Liver
_xdrug effects
650 0 4 _aPyrroles
_xblood
650 0 4 _aPyrrolidines
650 0 4 _aRats
650 0 4 _aRats, Wistar
650 0 4 _aVorinostat
700 1 _aGoh, Evelyn
700 1 _aZeng, Peizi
700 1 _aNew, Lee Sun
700 1 _aXin, Liu
700 1 _aPasha, Mohammed Khalid
700 1 _aSangthongpitag, Kanda
700 1 _aYeo, Pauline
700 1 _aKantharaj, Ethirajulu
773 0 _tBiological & pharmaceutical bulletin
_gvol. 30
_gno. 5
_gp. 1021-4
856 4 0 _uhttps://doi.org/10.1248/bpb.30.1021
_zAvailable from publisher's website
999 _c17021310
_d17021310