000 01796 a2200517 4500
005 20250511201051.0
264 0 _c19900830
008 199008s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm00170a009
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTurconi, M
245 0 0 _aSynthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cAug 1990
300 _a2101-8 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAnimals
650 0 4 _aBenzimidazoles
_xchemical synthesis
650 0 4 _aBinding, Competitive
650 0 4 _aBridged Bicyclo Compounds
_xchemical synthesis
650 0 4 _aBridged Bicyclo Compounds, Heterocyclic
650 0 4 _aBridged-Ring Compounds
_xpharmacology
650 0 4 _aCerebral Cortex
_xmetabolism
650 0 4 _aChemical Phenomena
650 0 4 _aChemistry
650 0 4 _aComputer Simulation
650 0 4 _aHydrogen Bonding
650 0 4 _aIndoles
_xmetabolism
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aRadioligand Assay
650 0 4 _aRats
650 0 4 _aReceptors, Serotonin
_xmetabolism
650 0 4 _aReflex
_xdrug effects
650 0 4 _aSerotonin Antagonists
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTropisetron
700 1 _aNicola, M
700 1 _aQuintero, M G
700 1 _aMaiocchi, L
700 1 _aMicheletti, R
700 1 _aGiraldo, E
700 1 _aDonetti, A
773 0 _tJournal of medicinal chemistry
_gvol. 33
_gno. 8
_gp. 2101-8
856 4 0 _uhttps://doi.org/10.1021/jm00170a009
_zAvailable from publisher's website
999 _c1702084
_d1702084