000 02222 a2200625 4500
005 20250515064715.0
264 0 _c20071019
008 200710s 0 0 eng d
022 _a0006-4971
024 7 _a10.1182/blood-2006-12-060814
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhang, Fang
245 0 0 _aLentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells.
_h[electronic resource]
260 _bBlood
_cSep 2007
300 _a1448-57 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aChromatin
_xgenetics
650 0 4 _aChromosomal Proteins, Non-Histone
_xgenetics
650 0 4 _aCytomegalovirus
_xgenetics
650 0 4 _aDisease Models, Animal
650 0 4 _aEnhancer Elements, Genetic
650 0 4 _aGene Expression
650 0 4 _aGene Silencing
650 0 4 _aGenetic Therapy
650 0 4 _aGenetic Vectors
650 0 4 _aGenome, Viral
_xgenetics
650 0 4 _aHeLa Cells
650 0 4 _aHematopoietic Stem Cells
650 0 4 _aHeterogeneous-Nuclear Ribonucleoprotein Group A-B
_xgenetics
650 0 4 _aHumans
650 0 4 _aInterleukin-2
_xgenetics
650 0 4 _aK562 Cells
650 0 4 _aLentivirus
_xgenetics
650 0 4 _aMice
650 0 4 _aMice, SCID
650 0 4 _aPromoter Regions, Genetic
_xgenetics
650 0 4 _aSignal Transduction
_xgenetics
650 0 4 _aSpleen Focus-Forming Viruses
_xgenetics
650 0 4 _aTransduction, Genetic
650 0 4 _aTransgenes
_xphysiology
650 0 4 _aVirus Integration
_xgenetics
650 0 4 _aX-Linked Combined Immunodeficiency Diseases
_xgenetics
700 1 _aThornhill, Susannah I
700 1 _aHowe, Steven J
700 1 _aUlaganathan, Meera
700 1 _aSchambach, Axel
700 1 _aSinclair, Joanna
700 1 _aKinnon, Christine
700 1 _aGaspar, H Bobby
700 1 _aAntoniou, Michael
700 1 _aThrasher, Adrian J
773 0 _tBlood
_gvol. 110
_gno. 5
_gp. 1448-57
856 4 0 _uhttps://doi.org/10.1182/blood-2006-12-060814
_zAvailable from publisher's website
999 _c17005993
_d17005993