000			02169 a2200553 4500
005			20250515063442.0
264		0	_c20070622
008			200706s 0 0 eng d
022			_a0731-7085
024	7		_a10.1016/j.jpba.2007.02.034 _2doi
040			_aNLM _beng _cNLM
100	1		_aYao, Ming
245	0	0	_aDevelopment and full validation of six inhibition assays for five major cytochrome P450 enzymes in human liver microsomes using an automated 96-well microplate incubation format and LC-MS/MS analysis. _h[electronic resource]
260			_bJournal of pharmaceutical and biomedical analysis _cMay 2007
300			_a211-23 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAryl Hydrocarbon Hydroxylases _xantagonists & inhibitors
650	0	4	_aAutoanalysis
650	0	4	_aBiological Assay
650	0	4	_aChromatography, Liquid _xmethods
650	0	4	_aCytochrome P-450 CYP1A2 _xchemistry
650	0	4	_aCytochrome P-450 CYP1A2 Inhibitors
650	0	4	_aCytochrome P-450 CYP2C19
650	0	4	_aCytochrome P-450 CYP2C9
650	0	4	_aCytochrome P-450 CYP2D6 _xchemistry
650	0	4	_aCytochrome P-450 CYP2D6 Inhibitors
650	0	4	_aCytochrome P-450 CYP3A
650	0	4	_aCytochrome P-450 Enzyme Inhibitors
650	0	4	_aCytochrome P-450 Enzyme System _xchemistry
650	0	4	_aEnzyme Inhibitors _xpharmacology
650	0	4	_aHumans
650	0	4	_aInhibitory Concentration 50
650	0	4	_aIsoenzymes _xantagonists & inhibitors
650	0	4	_aKinetics
650	0	4	_aMicrosomes, Liver _xenzymology
650	0	4	_aMixed Function Oxygenases _xantagonists & inhibitors
650	0	4	_aMolecular Structure
650	0	4	_aReproducibility of Results
650	0	4	_aSubstrate Specificity
650	0	4	_aTandem Mass Spectrometry _xmethods
700	1		_aZhu, Mingshe
700	1		_aSinz, Michael W
700	1		_aZhang, Hongjian
700	1		_aHumphreys, W Griffith
700	1		_aRodrigues, A David
700	1		_aDai, Renke
773	0		_tJournal of pharmaceutical and biomedical analysis _gvol. 44 _gno. 1 _gp. 211-23
856	4	0	_uhttps://doi.org/10.1016/j.jpba.2007.02.034 _zAvailable from publisher's website
999			_c16970116 _d16970116