000			02346 a2200685 4500
005			20250515061057.0
264		0	_c20070926
008			200709s 0 0 eng d
022			_a0009-9236
024	7		_a10.1038/sj.clpt.6100138 _2doi
040			_aNLM _beng _cNLM
100	1		_aSaussele, T
245	0	0	_aSelective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole. _h[electronic resource]
260			_bClinical pharmacology and therapeutics _cSep 2007
300			_a265-74 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAged
650	0	4	_aAnti-Inflammatory Agents, Non-Steroidal _xpharmacology
650	0	4	_aAryl Hydrocarbon Hydroxylases _xbiosynthesis
650	0	4	_aBlotting, Western
650	0	4	_aCatalysis
650	0	4	_aCells, Cultured
650	0	4	_aConstitutive Androstane Receptor
650	0	4	_aCytochrome P-450 CYP2B6
650	0	4	_aCytochrome P-450 CYP3A
650	0	4	_aCytochrome P-450 Enzyme System _xbiosynthesis
650	0	4	_aDNA _xbiosynthesis
650	0	4	_aDipyrone _xanalogs & derivatives
650	0	4	_aDose-Response Relationship, Drug
650	0	4	_aEnzyme Induction _xdrug effects
650	0	4	_aFemale
650	0	4	_aGenotype
650	0	4	_aHepatocytes _xdrug effects
650	0	4	_aHumans
650	0	4	_aIn Vitro Techniques
650	0	4	_aIsoenzymes _xmetabolism
650	0	4	_aLiver _xdrug effects
650	0	4	_aMale
650	0	4	_aMicrosomes, Liver _xdrug effects
650	0	4	_aMiddle Aged
650	0	4	_aOxidoreductases, N-Demethylating _xbiosynthesis
650	0	4	_aPlasmids
650	0	4	_aPregnane X Receptor
650	0	4	_aRNA _xbiosynthesis
650	0	4	_aReceptors, Cytoplasmic and Nuclear _xdrug effects
650	0	4	_aReceptors, Steroid _xdrug effects
650	0	4	_aReverse Transcriptase Polymerase Chain Reaction
650	0	4	_aTranscription Factors _xdrug effects
700	1		_aBurk, O
700	1		_aBlievernicht, J K
700	1		_aKlein, K
700	1		_aNussler, A
700	1		_aNussler, N
700	1		_aHengstler, J G
700	1		_aEichelbaum, M
700	1		_aSchwab, M
700	1		_aZanger, U M
773	0		_tClinical pharmacology and therapeutics _gvol. 82 _gno. 3 _gp. 265-74
856	4	0	_uhttps://doi.org/10.1038/sj.clpt.6100138 _zAvailable from publisher's website
999			_c16901453 _d16901453