000 01836 a2200517 4500
005 20250515060456.0
264 0 _c20070427
008 200704s 0 0 eng d
022 _a0022-2623
024 7 _a10.1021/jm061062o
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAtwell, Graham J
245 0 0 _aSynthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cMar 2007
300 _a1197-212 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents, Alkylating
_xchemical synthesis
650 0 4 _aBystander Effect
650 0 4 _aCell Line, Tumor
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aEnzyme Activation
650 0 4 _aEscherichia coli Proteins
_xgenetics
650 0 4 _aFemale
650 0 4 _aGenetic Therapy
650 0 4 _aHumans
650 0 4 _aLeast-Squares Analysis
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMultivariate Analysis
650 0 4 _aNitrogen Mustard Compounds
_xchemical synthesis
650 0 4 _aNitroreductases
_xgenetics
650 0 4 _aProdrugs
_xchemical synthesis
650 0 4 _aQuantitative Structure-Activity Relationship
650 0 4 _aTransplantation, Heterologous
700 1 _aYang, Shangjin
700 1 _aPruijn, Frederik B
700 1 _aPullen, Susan M
700 1 _aHogg, Alison
700 1 _aPatterson, Adam V
700 1 _aWilson, William R
700 1 _aDenny, William A
773 0 _tJournal of medicinal chemistry
_gvol. 50
_gno. 6
_gp. 1197-212
856 4 0 _uhttps://doi.org/10.1021/jm061062o
_zAvailable from publisher's website
999 _c16884283
_d16884283