000 01730 a2200529 4500
005 20250515055718.0
264 0 _c20070425
008 200704s 0 0 eng d
022 _a0009-9236
024 7 _a10.1038/sj.clpt.6100084
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHamberg, A-K
245 0 0 _aA PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy.
_h[electronic resource]
260 _bClinical pharmacology and therapeutics
_cApr 2007
300 _a529-38 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAging
_xmetabolism
650 0 4 _aAlgorithms
650 0 4 _aAnticoagulants
_xadministration & dosage
650 0 4 _aAryl Hydrocarbon Hydroxylases
_xgenetics
650 0 4 _aCytochrome P-450 CYP2C9
650 0 4 _aDNA
_xgenetics
650 0 4 _aDatabases, Factual
650 0 4 _aFemale
650 0 4 _aGenotype
650 0 4 _aHumans
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aMixed Function Oxygenases
_xgenetics
650 0 4 _aModels, Statistical
650 0 4 _aPharmacokinetics
650 0 4 _aPopulation
650 0 4 _aStereoisomerism
650 0 4 _aVitamin K Epoxide Reductases
650 0 4 _aWarfarin
_xadministration & dosage
700 1 _aDahl, M-L
700 1 _aBarban, M
700 1 _aScordo, M G
700 1 _aWadelius, M
700 1 _aPengo, V
700 1 _aPadrini, R
700 1 _aJonsson, E N
773 0 _tClinical pharmacology and therapeutics
_gvol. 81
_gno. 4
_gp. 529-38
856 4 0 _uhttps://doi.org/10.1038/sj.clpt.6100084
_zAvailable from publisher's website
999 _c16861094
_d16861094