| 000 | 01771 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250515054859.0 | ||
| 264 | 0 | _c20070530 | |
| 008 | 200705s 0 0 eng d | ||
| 022 | _a0960-894X | ||
| 024 | 7 |
_a10.1016/j.bmcl.2007.01.048 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aMartin, Matthew W | |
| 245 | 0 | 0 |
_aDiscovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _cApr 2007 |
||
| 300 |
_a2299-304 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAmines _xchemical synthesis |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aInhibitory Concentration 50 |
| 650 | 0 | 4 |
_aLymphocyte Specific Protein Tyrosine Kinase p56(lck) _xantagonists & inhibitors |
| 650 | 0 | 4 | _aPharmacokinetics |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xchemical synthesis |
| 650 | 0 | 4 |
_aPyridines _xchemical synthesis |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aNewcomb, John | |
| 700 | 1 | _aNunes, Joseph J | |
| 700 | 1 | _aBemis, Jean E | |
| 700 | 1 | _aMcGowan, David C | |
| 700 | 1 | _aWhite, Ryan D | |
| 700 | 1 | _aBuchanan, John L | |
| 700 | 1 | _aDiMauro, Erin F | |
| 700 | 1 | _aBoucher, Christina | |
| 700 | 1 | _aFaust, Theodore | |
| 700 | 1 | _aHsieh, Faye | |
| 700 | 1 | _aHuang, Xin | |
| 700 | 1 | _aLee, Josie H | |
| 700 | 1 | _aSchneider, Stephen | |
| 700 | 1 | _aTurci, Susan M | |
| 700 | 1 | _aZhu, Xiaotian | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 17 _gno. 8 _gp. 2299-304 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2007.01.048 _zAvailable from publisher's website |
| 999 |
_c16837315 _d16837315 |
||