000			02063 a2200589 4500
005			20250515054258.0
264		0	_c20070529
008			200705s 0 0 eng d
022			_a0960-894X
024	7		_a10.1016/j.bmcl.2006.12.051 _2doi
040			_aNLM _beng _cNLM
100	1		_aStauffer, Shaun R
245	0	0	_aDiscovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. _h[electronic resource]
260			_bBioorganic & medicinal chemistry letters _cMar 2007
300			_a1788-92 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAmyloid Precursor Protein Secretases _xantagonists & inhibitors
650	0	4	_aAnimals
650	0	4	_aAspartic Acid Endopeptidases _xantagonists & inhibitors
650	0	4	_aBaculoviridae _xdrug effects
650	0	4	_aBiological Availability
650	0	4	_aCells, Cultured
650	0	4	_aEnzyme Inhibitors _xchemical synthesis
650	0	4	_aMagnetic Resonance Spectroscopy
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Conformation
650	0	4	_aMolecular Weight
650	0	4	_aNiacinamide _xchemical synthesis
650	0	4	_aRats
650	0	4	_aStructure-Activity Relationship
700	1		_aStanton, Matthew G
700	1		_aGregro, Alison R
700	1		_aSteinbeiser, Melissa A
700	1		_aShaffer, Jennifer R
700	1		_aNantermet, Philippe G
700	1		_aBarrow, James C
700	1		_aRittle, Kenneth E
700	1		_aCollusi, Dennis
700	1		_aEspeseth, Amy S
700	1		_aLai, Ming-Tain
700	1		_aPietrak, Beth L
700	1		_aHolloway, M Katharine
700	1		_aMcGaughey, Georgia B
700	1		_aMunshi, Sanjeev K
700	1		_aHochman, Jerome H
700	1		_aSimon, Adam J
700	1		_aSelnick, Harold G
700	1		_aGraham, Samuel L
700	1		_aVacca, Joseph P
773	0		_tBioorganic & medicinal chemistry letters _gvol. 17 _gno. 6 _gp. 1788-92
856	4	0	_uhttps://doi.org/10.1016/j.bmcl.2006.12.051 _zAvailable from publisher's website
999			_c16819713 _d16819713