000 02513 a2200673 4500
005 20250515054123.0
264 0 _c20070413
008 200704s 0 0 eng d
022 _a0887-6924
024 7 _a10.1038/sj.leu.2404533
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBarnes, D J
245 0 0 _aDifferent target range and cytotoxic specificity of adaphostin and 17-allylamino-17-demethoxygeldanamycin in imatinib-resistant and sensitive cell lines.
_h[electronic resource]
260 _bLeukemia
_cMar 2007
300 _a421-6 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAdamantane
_xadverse effects
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBenzamides
650 0 4 _aBenzoquinones
_xadverse effects
650 0 4 _aCell Line, Transformed
_xdrug effects
650 0 4 _aCell Line, Tumor
_xdrug effects
650 0 4 _aClone Cells
_xdrug effects
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aFusion Proteins, bcr-abl
_xantagonists & inhibitors
650 0 4 _aGene Expression Regulation, Leukemic
_xdrug effects
650 0 4 _aGenes, abl
650 0 4 _aHSP90 Heat-Shock Proteins
_xphysiology
650 0 4 _aHumans
650 0 4 _aHydrogen Peroxide
_xpharmacology
650 0 4 _aHydroquinones
_xadverse effects
650 0 4 _aImatinib Mesylate
650 0 4 _aLactams, Macrocyclic
_xadverse effects
650 0 4 _aMice
650 0 4 _aMutant Proteins
_xgenetics
650 0 4 _aMutation, Missense
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aPoint Mutation
650 0 4 _aProtein Kinase Inhibitors
_xadverse effects
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aProto-Oncogene Proteins c-akt
_xbiosynthesis
650 0 4 _aProto-Oncogene Proteins c-bcr
_xbiosynthesis
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aReactive Oxygen Species
650 0 4 _aRecombinant Fusion Proteins
_xgenetics
650 0 4 _aSTAT5 Transcription Factor
_xbiosynthesis
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSubstrate Specificity
650 0 4 _aTransfection
700 1 _aDe, S
700 1 _avan Hensbergen, P
700 1 _aMoravcsik, E
700 1 _aMelo, J V
773 0 _tLeukemia
_gvol. 21
_gno. 3
_gp. 421-6
856 4 0 _uhttps://doi.org/10.1038/sj.leu.2404533
_zAvailable from publisher's website
999 _c16814497
_d16814497