000			02162 a2200577 4500
005			20250515052009.0
264		0	_c20070202
008			200702s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm061108d _2doi
040			_aNLM _beng _cNLM
100	1		_aSun, Haiying
245	0	0	_aDesign, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic. _h[electronic resource]
260			_bJournal of medicinal chemistry _cDec 2006
300			_a7916-20 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAzepines _xchemical synthesis
650	0	4	_aBaculoviral IAP Repeat-Containing 3 Protein
650	0	4	_aBinding, Competitive
650	0	4	_aBreast Neoplasms _xmetabolism
650	0	4	_aCaspase 3 _xmetabolism
650	0	4	_aCaspase 9 _xmetabolism
650	0	4	_aCaspase Inhibitors
650	0	4	_aCell Death _xdrug effects
650	0	4	_aCell Membrane Permeability
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aEnzyme Activation _xdrug effects
650	0	4	_aHeterocyclic Compounds _xchemical synthesis
650	0	4	_aHumans
650	0	4	_aInhibitor of Apoptosis Proteins _xmetabolism
650	0	4	_aMitochondria _xdrug effects
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Conformation
650	0	4	_aMolecular Mimicry
650	0	4	_aProtein Binding
650	0	4	_aPyrrolidines _xchemical synthesis
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTumor Cells, Cultured
650	0	4	_aUbiquitin-Protein Ligases
650	0	4	_aX-Linked Inhibitor of Apoptosis Protein _xmetabolism
700	1		_aNikolovska-Coleska, Zaneta
700	1		_aLu, Jianfeng
700	1		_aQiu, Su
700	1		_aYang, Chao-Yie
700	1		_aGao, Wei
700	1		_aMeagher, Jennifer
700	1		_aStuckey, Jeanne
700	1		_aWang, Shaomeng
773	0		_tJournal of medicinal chemistry _gvol. 49 _gno. 26 _gp. 7916-20
856	4	0	_uhttps://doi.org/10.1021/jm061108d _zAvailable from publisher's website
999			_c16748904 _d16748904