000 01724 a2200529 4500
005 20250515051452.0
264 0 _c20070220
008 200702s 0 0 eng d
022 _a0002-7863
024 7 _a10.1021/ja0646491
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aMagis, C
245 0 0 _aStructure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
_h[electronic resource]
260 _bJournal of the American Chemical Society
_cDec 2006
300 _a16190-205 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAmino Acid Sequence
650 0 4 _aComputational Biology
650 0 4 _aCrystallography, X-Ray
650 0 4 _aKv1.2 Potassium Channel
_xchemistry
650 0 4 _aLigands
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Sequence Data
650 0 4 _aMutation
_xgenetics
650 0 4 _aPotassium Channel Blockers
_xchemistry
650 0 4 _aProtein Binding
650 0 4 _aProtein Structure, Secondary
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aSequence Alignment
650 0 4 _aStatic Electricity
700 1 _aGasparini, D
700 1 _aLecoq, A
700 1 _aLe Du, M H
700 1 _aStura, E
700 1 _aCharbonnier, J B
700 1 _aMourier, G
700 1 _aBoulain, J-C
700 1 _aPardo, L
700 1 _aCaruana, A
700 1 _aJoly, A
700 1 _aLefranc, M
700 1 _aMasella, M
700 1 _aMenez, A
700 1 _aCuniasse, P
773 0 _tJournal of the American Chemical Society
_gvol. 128
_gno. 50
_gp. 16190-205
856 4 0 _uhttps://doi.org/10.1021/ja0646491
_zAvailable from publisher's website
999 _c16734175
_d16734175