000 02195 a2200577 4500
005 20250515051223.0
264 0 _c20070215
008 200702s 0 0 eng d
022 _a0891-5849
024 7 _a10.1016/j.freeradbiomed.2006.09.018
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aCai, Ying
245 0 0 _aIncreased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation.
_h[electronic resource]
260 _bFree radical biology & medicine
_cJan 2007
300 _a64-78 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAMP-Activated Protein Kinases
650 0 4 _aAminoimidazole Carboxamide
_xanalogs & derivatives
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xphysiology
650 0 4 _aBlotting, Western
650 0 4 _aCaspase 3
_xmetabolism
650 0 4 _aCell Line
650 0 4 _aEnzyme Activation
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aGlucose
_xpharmacology
650 0 4 _aHydrogen Peroxide
_xpharmacology
650 0 4 _aHypoglycemic Agents
_xmetabolism
650 0 4 _aInsulin
_xmetabolism
650 0 4 _aInsulin-Secreting Cells
_xmetabolism
650 0 4 _aJNK Mitogen-Activated Protein Kinases
_xmetabolism
650 0 4 _aMice
650 0 4 _aMitochondria
_xmetabolism
650 0 4 _aMultienzyme Complexes
_xmetabolism
650 0 4 _aPalmitates
_xpharmacology
650 0 4 _aPhosphorylation
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xmetabolism
650 0 4 _aRNA, Messenger
_xgenetics
650 0 4 _aRats
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aRibonucleotides
_xpharmacology
700 1 _aMartens, Geert A
700 1 _aHinke, Simon A
700 1 _aHeimberg, Harry
700 1 _aPipeleers, Daniel
700 1 _aVan de Casteele, Mark
773 0 _tFree radical biology & medicine
_gvol. 42
_gno. 1
_gp. 64-78
856 4 0 _uhttps://doi.org/10.1016/j.freeradbiomed.2006.09.018
_zAvailable from publisher's website
999 _c16726072
_d16726072