000 01682 a2200457 4500
005 20250511195523.0
264 0 _c19910904
008 199109s 0 0 eng d
022 _a0027-8424
024 7 _a10.1073/pnas.88.15.6775
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWu, Q Y
245 0 0 _aSingle amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin.
_h[electronic resource]
260 _bProceedings of the National Academy of Sciences of the United States of America
_cAug 1991
300 _a6775-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAmino Acid Sequence
650 0 4 _aAnimals
650 0 4 _aCell Line
650 0 4 _aComputer Simulation
650 0 4 _aFibrinogen
_xmetabolism
650 0 4 _aHumans
650 0 4 _aKinetics
650 0 4 _aModels, Molecular
650 0 4 _aMutagenesis, Site-Directed
650 0 4 _aPlatelet Aggregation
_xdrug effects
650 0 4 _aProtein Conformation
650 0 4 _aProthrombin
_xgenetics
650 0 4 _aReceptors, Cell Surface
_xmetabolism
650 0 4 _aReceptors, Thrombin
650 0 4 _aRecombinant Proteins
_xmetabolism
650 0 4 _aThrombin
_xgenetics
650 0 4 _aTransfection
700 1 _aSheehan, J P
700 1 _aTsiang, M
700 1 _aLentz, S R
700 1 _aBirktoft, J J
700 1 _aSadler, J E
773 0 _tProceedings of the National Academy of Sciences of the United States of America
_gvol. 88
_gno. 15
_gp. 6775-9
856 4 0 _uhttps://doi.org/10.1073/pnas.88.15.6775
_zAvailable from publisher's website
999 _c1656959
_d1656959