| 000 | 01340 a2200325 4500 | ||
|---|---|---|---|
| 005 | 20250515041928.0 | ||
| 264 | 0 | _c20070212 | |
| 008 | 200702s 0 0 eng d | ||
| 022 | _a0090-9556 | ||
| 024 | 7 |
_a10.1124/dmd.106.012054 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aKumar, Santosh | |
| 245 | 0 | 0 |
_aEngineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesis. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cDec 2006 |
||
| 300 |
_a1958-65 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural | ||
| 650 | 0 | 4 |
_aBenzene Derivatives _xchemistry |
| 650 | 0 | 4 |
_aCoumarins _xmetabolism |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP3A _xgenetics |
| 650 | 0 | 4 | _aDirected Molecular Evolution |
| 650 | 0 | 4 |
_aHydrogen Peroxide _xchemistry |
| 650 | 0 | 4 | _aMutagenesis, Site-Directed |
| 650 | 0 | 4 | _aOxidation-Reduction |
| 650 | 0 | 4 |
_aQuinolines _xmetabolism |
| 650 | 0 | 4 |
_aTestosterone _xmetabolism |
| 700 | 1 | _aLiu, Hong | |
| 700 | 1 | _aHalpert, James R | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 34 _gno. 12 _gp. 1958-65 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.106.012054 _zAvailable from publisher's website |
| 999 |
_c16566650 _d16566650 |
||