000 02291 a2200601 4500
005 20250515041613.0
264 0 _c20070123
008 200701s 0 0 eng d
022 _a0969-9961
024 7 _a10.1016/j.nbd.2006.07.005
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFernandez-Gomez, F J
245 0 0 _aPyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression.
_h[electronic resource]
260 _bNeurobiology of disease
_cNov 2006
300 _a296-307 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAnimals, Newborn
650 0 4 _aAntioxidants
_xmetabolism
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aCerebellar Cortex
_xdrug effects
650 0 4 _aCytoprotection
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aExtracellular Signal-Regulated MAP Kinases
_xdrug effects
650 0 4 _aGlutathione Peroxidase
_xdrug effects
650 0 4 _aLipid Peroxidation
_xdrug effects
650 0 4 _aNerve Degeneration
_xdrug therapy
650 0 4 _aNeurons
_xdrug effects
650 0 4 _aNeuroprotective Agents
_xmetabolism
650 0 4 _aNeurotoxins
_xantagonists & inhibitors
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aOxidopamine
_xantagonists & inhibitors
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aProto-Oncogene Proteins c-akt
_xdrug effects
650 0 4 _aPyruvic Acid
_xmetabolism
650 0 4 _aRNA, Messenger
_xdrug effects
650 0 4 _aRats
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aUp-Regulation
_xdrug effects
700 1 _aPastor, M D
700 1 _aGarcia-Martinez, E M
700 1 _aMelero-Fernandez de Mera, R
700 1 _aGou-Fabregas, M
700 1 _aGomez-Lazaro, M
700 1 _aCalvo, S
700 1 _aSoler, R M
700 1 _aGalindo, M F
700 1 _aJordán, J
773 0 _tNeurobiology of disease
_gvol. 24
_gno. 2
_gp. 296-307
856 4 0 _uhttps://doi.org/10.1016/j.nbd.2006.07.005
_zAvailable from publisher's website
999 _c16558006
_d16558006