| 000 | 02913 a2200937 4500 | ||
|---|---|---|---|
| 005 | 20250515041436.0 | ||
| 264 | 0 | _c20061024 | |
| 008 | 200610s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm0605482 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aDiMauro, Erin F | |
| 245 | 0 | 0 |
_aDiscovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cSep 2006 |
||
| 300 |
_a5671-86 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAnti-Inflammatory Agents, Non-Steroidal _xchemical synthesis |
| 650 | 0 | 4 |
_aBenzamides _xchemical synthesis |
| 650 | 0 | 4 | _aBiological Availability |
| 650 | 0 | 4 |
_aCell Proliferation _xdrug effects |
| 650 | 0 | 4 | _aCells, Cultured |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aIn Vitro Techniques |
| 650 | 0 | 4 |
_aInterleukin-2 _xbiosynthesis |
| 650 | 0 | 4 |
_aLymphocyte Specific Protein Tyrosine Kinase p56(lck) _xantagonists & inhibitors |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMice, Inbred BALB C |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 |
_aQuinazolines _xchemical synthesis |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aT-Lymphocytes _xcytology |
| 650 | 0 | 4 |
_aTumor Necrosis Factor-alpha _xbiosynthesis |
| 700 | 1 | _aNewcomb, John | |
| 700 | 1 | _aNunes, Joseph J | |
| 700 | 1 | _aBemis, Jean E | |
| 700 | 1 | _aBoucher, Christina | |
| 700 | 1 | _aBuchanan, John L | |
| 700 | 1 | _aBuckner, William H | |
| 700 | 1 | _aCee, Victor J | |
| 700 | 1 | _aChai, Lilly | |
| 700 | 1 | _aDeak, Holly L | |
| 700 | 1 | _aEpstein, Linda F | |
| 700 | 1 | _aFaust, Ted | |
| 700 | 1 | _aGallant, Paul | |
| 700 | 1 | _aGeuns-Meyer, Stephanie D | |
| 700 | 1 | _aGore, Anu | |
| 700 | 1 | _aGu, Yan | |
| 700 | 1 | _aHenkle, Brad | |
| 700 | 1 | _aHodous, Brian L | |
| 700 | 1 | _aHsieh, Faye | |
| 700 | 1 | _aHuang, Xin | |
| 700 | 1 | _aKim, Joseph L | |
| 700 | 1 | _aLee, Josie H | |
| 700 | 1 | _aMartin, Matthew W | |
| 700 | 1 | _aMasse, Craig E | |
| 700 | 1 | _aMcGowan, David C | |
| 700 | 1 | _aMetz, Daniela | |
| 700 | 1 | _aMohn, Deanna | |
| 700 | 1 | _aMorgenstern, Kurt A | |
| 700 | 1 | _aOliveira-dos-Santos, Antonio | |
| 700 | 1 | _aPatel, Vinod F | |
| 700 | 1 | _aPowers, David | |
| 700 | 1 | _aRose, Paul E | |
| 700 | 1 | _aSchneider, Stephen | |
| 700 | 1 | _aTomlinson, Susan A | |
| 700 | 1 | _aTudor, Yan-Yan | |
| 700 | 1 | _aTurci, Susan M | |
| 700 | 1 | _aWelcher, Andrew A | |
| 700 | 1 | _aWhite, Ryan D | |
| 700 | 1 | _aZhao, Huilin | |
| 700 | 1 | _aZhu, Li | |
| 700 | 1 | _aZhu, Xiaotian | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 49 _gno. 19 _gp. 5671-86 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm0605482 _zAvailable from publisher's website |
| 999 |
_c16552854 _d16552854 |
||