000 02766 a2200781 4500
005 20250515040732.0
264 0 _c20070109
008 200701s 0 0 eng d
022 _a0022-3565
024 7 _a10.1124/jpet.106.109058
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBraselmann, Sylvia
245 0 0 _aR406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cDec 2006
300 _a998-1008 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntigen-Antibody Complex
_xphysiology
650 0 4 _aArthritis, Experimental
_xpathology
650 0 4 _aArthus Reaction
_xphysiopathology
650 0 4 _aB-Lymphocytes
_xdrug effects
650 0 4 _aBasophils
_xdrug effects
650 0 4 _aBlotting, Western
650 0 4 _aCells, Cultured
650 0 4 _aCrystallography
650 0 4 _aDouble-Blind Method
650 0 4 _aEnzyme Inhibitors
_xpharmacokinetics
650 0 4 _aFluorescence Polarization Immunoassay
650 0 4 _aHumans
650 0 4 _aImmunoglobulin G
_xbiosynthesis
650 0 4 _aInflammation
_xdrug therapy
650 0 4 _aLipopolysaccharides
_xpharmacology
650 0 4 _aMacrophages
_xdrug effects
650 0 4 _aMast Cells
_xdrug effects
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aOxazines
_xpharmacokinetics
650 0 4 _aPlatelet Aggregation
_xdrug effects
650 0 4 _aProtein-Tyrosine Kinases
_xantagonists & inhibitors
650 0 4 _aPyridines
_xpharmacokinetics
650 0 4 _aReceptors, Fc
_xantagonists & inhibitors
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aSpleen
_xenzymology
650 0 4 _aStimulation, Chemical
650 0 4 _aTetradecanoylphorbol Acetate
_xpharmacology
700 1 _aTaylor, Vanessa
700 1 _aZhao, Haoran
700 1 _aWang, Su
700 1 _aSylvain, Catherine
700 1 _aBaluom, Muhammad
700 1 _aQu, Kunbin
700 1 _aHerlaar, Ellen
700 1 _aLau, Angela
700 1 _aYoung, Chi
700 1 _aWong, Brian R
700 1 _aLovell, Scott
700 1 _aSun, Thomas
700 1 _aPark, Gary
700 1 _aArgade, Ankush
700 1 _aJurcevic, Stipo
700 1 _aPine, Polly
700 1 _aSingh, Rajinder
700 1 _aGrossbard, Elliott B
700 1 _aPayan, Donald G
700 1 _aMasuda, Esteban S
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 319
_gno. 3
_gp. 998-1008
856 4 0 _uhttps://doi.org/10.1124/jpet.106.109058
_zAvailable from publisher's website
999 _c16531195
_d16531195