000 01989 a2200529 4500
005 20250515034922.0
264 0 _c20061102
008 200611s 0 0 eng d
022 _a0960-894X
024 7 _a10.1016/j.bmcl.2006.07.031
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSmith, Leon
245 0 0 _aNovel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cOct 2006
300 _a5102-6 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aAzepines
_xchemical synthesis
650 0 4 _aCell Line, Tumor
650 0 4 _aErbB Receptors
_xantagonists & inhibitors
650 0 4 _aHeterocyclic Compounds, 3-Ring
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aInhibitory Concentration 50
650 0 4 _aNeoplasm Proteins
_xantagonists & inhibitors
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aStructure-Activity Relationship
650 0 4 _aVascular Endothelial Growth Factor Receptor-2
_xantagonists & inhibitors
700 1 _aWong, Wai C
700 1 _aKiselyov, Alexander S
700 1 _aBurdzovic-Wizemann, Sabina
700 1 _aMao, Yunyu
700 1 _aXu, Yongjiang
700 1 _aDuncton, Matthew A J
700 1 _aKim, Ki
700 1 _aPiatnitski, Evgueni L
700 1 _aDoody, Jacqueline F
700 1 _aWang, Ying
700 1 _aRosler, Robin L
700 1 _aMilligan, Daniel
700 1 _aColumbus, John
700 1 _aBalagtas, Chris
700 1 _aLee, Sui Ping
700 1 _aKonovalov, Andrey
700 1 _aHadari, Yaron R
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 16
_gno. 19
_gp. 5102-6
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2006.07.031
_zAvailable from publisher's website
999 _c16475781
_d16475781