000 01716 a2200469 4500
005 20250515033121.0
264 0 _c20061114
008 200611s 0 0 eng d
022 _a0731-7085
024 7 _a10.1016/j.jpba.2006.05.008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYu, Lei
245 0 0 _aInvestigation of N-terminal glutamate cyclization of recombinant monoclonal antibody in formulation development.
_h[electronic resource]
260 _bJournal of pharmaceutical and biomedical analysis
_cOct 2006
300 _a455-63 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article
650 0 4 _aAmino Acid Sequence
650 0 4 _aAntibodies, Monoclonal
_xchemistry
650 0 4 _aChemistry, Pharmaceutical
650 0 4 _aChromatography, High Pressure Liquid
650 0 4 _aCyclization
650 0 4 _aDrug Stability
650 0 4 _aExcipients
_xchemistry
650 0 4 _aGlutamic Acid
_xchemistry
650 0 4 _aHydrogen-Ion Concentration
650 0 4 _aKinetics
650 0 4 _aMolecular Sequence Data
650 0 4 _aProtein Conformation
650 0 4 _aProtein Denaturation
650 0 4 _aPyrrolidonecarboxylic Acid
_xchemistry
650 0 4 _aRecombinant Proteins
_xchemistry
650 0 4 _aSpectrometry, Mass, Electrospray Ionization
_xmethods
650 0 4 _aSurface-Active Agents
_xchemistry
650 0 4 _aTemperature
700 1 _aVizel, Alona
700 1 _aHuff, Mary Beth
700 1 _aYoung, Meagan
700 1 _aRemmele, Richard L
700 1 _aHe, Bing
773 0 _tJournal of pharmaceutical and biomedical analysis
_gvol. 42
_gno. 4
_gp. 455-63
856 4 0 _uhttps://doi.org/10.1016/j.jpba.2006.05.008
_zAvailable from publisher's website
999 _c16419900
_d16419900