000			01999 a2200481 4500
005			20250515032522.0
264		0	_c20061102
008			200611s 0 0 eng d
022			_a0022-3565
024	7		_a10.1124/jpet.106.106096 _2doi
040			_aNLM _beng _cNLM
100	1		_aMoore, C S
245	0	0	_aPeripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis. _h[electronic resource]
260			_bThe Journal of pharmacology and experimental therapeutics _cOct 2006
300			_a63-72 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_a3',5'-Cyclic-AMP Phosphodiesterases _xantagonists & inhibitors
650	0	4	_aAnimals
650	0	4	_aBody Weight _xdrug effects
650	0	4	_aCyclic Nucleotide Phosphodiesterases, Type 4
650	0	4	_aEncephalomyelitis, Autoimmune, Experimental _xprevention & control
650	0	4	_aGlial Fibrillary Acidic Protein _xanalysis
650	0	4	_aLipopolysaccharides _xpharmacology
650	0	4	_aMice
650	0	4	_aMice, Inbred C57BL
650	0	4	_aMultiple Sclerosis _xdrug therapy
650	0	4	_aPhosphodiesterase Inhibitors _xtherapeutic use
650	0	4	_aProto-Oncogene Proteins c-fos _xanalysis
650	0	4	_aPyridines _xtherapeutic use
650	0	4	_aRolipram _xtherapeutic use
650	0	4	_aSpinal Cord _xpathology
650	0	4	_aTumor Necrosis Factor-alpha _xbiosynthesis
700	1		_aEarl, N
700	1		_aFrenette, R
700	1		_aStyhler, A
700	1		_aMancini, J A
700	1		_aNicholson, D W
700	1		_aHebb, A L O
700	1		_aOwens, T
700	1		_aRobertson, G S
773	0		_tThe Journal of pharmacology and experimental therapeutics _gvol. 319 _gno. 1 _gp. 63-72
856	4	0	_uhttps://doi.org/10.1124/jpet.106.106096 _zAvailable from publisher's website
999			_c16402269 _d16402269