000			02129 a2200625 4500
005			20250515014915.0
264		0	_c20060221
008			200602s 0 0 eng d
022			_a1533-4406
024	7		_a10.1056/NEJMoa050580 _2doi
040			_aNLM _beng _cNLM
100	1		_aBerry, Mike A
245	0	0	_aEvidence of a role of tumor necrosis factor alpha in refractory asthma. _h[electronic resource]
260			_bThe New England journal of medicine _cFeb 2006
300			_a697-708 p. _bdigital
500			_aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650	0	4	_aADAM Proteins _xbiosynthesis
650	0	4	_aADAM17 Protein
650	0	4	_aAdolescent
650	0	4	_aAdult
650	0	4	_aAged
650	0	4	_aAsthma _xdrug therapy
650	0	4	_aBiomarkers _xmetabolism
650	0	4	_aBronchial Hyperreactivity _xdrug therapy
650	0	4	_aCase-Control Studies
650	0	4	_aCross-Over Studies
650	0	4	_aDouble-Blind Method
650	0	4	_aEtanercept
650	0	4	_aFemale
650	0	4	_aForced Expiratory Volume _xdrug effects
650	0	4	_aHumans
650	0	4	_aImmunoglobulin G _xtherapeutic use
650	0	4	_aImmunologic Factors _xtherapeutic use
650	0	4	_aMale
650	0	4	_aMethacholine Chloride
650	0	4	_aMiddle Aged
650	0	4	_aMonocytes _xmetabolism
650	0	4	_aPilot Projects
650	0	4	_aReceptors, Tumor Necrosis Factor _xtherapeutic use
650	0	4	_aReceptors, Tumor Necrosis Factor, Type I _xbiosynthesis
650	0	4	_aTreatment Outcome
650	0	4	_aTumor Necrosis Factor-alpha _xantagonists & inhibitors
650	0	4	_aUp-Regulation
700	1		_aHargadon, Beverley
700	1		_aShelley, Maria
700	1		_aParker, Debbie
700	1		_aShaw, Dominick E
700	1		_aGreen, Ruth H
700	1		_aBradding, Peter
700	1		_aBrightling, Christopher E
700	1		_aWardlaw, Andrew J
700	1		_aPavord, Ian D
773	0		_tThe New England journal of medicine _gvol. 354 _gno. 7 _gp. 697-708
856	4	0	_uhttps://doi.org/10.1056/NEJMoa050580 _zAvailable from publisher's website
999			_c16093424 _d16093424