| 000 | 02515 a2200817 4500 | ||
|---|---|---|---|
| 005 | 20250515014714.0 | ||
| 264 | 0 | _c20060517 | |
| 008 | 200605s 0 0 eng d | ||
| 022 | _a1078-8956 | ||
| 024 | 7 |
_a10.1038/nm1358 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aManno, Catherine S | |
| 245 | 0 | 0 |
_aSuccessful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. _h[electronic resource] |
| 260 |
_bNature medicine _cMar 2006 |
||
| 300 |
_a342-7 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aDependovirus _xgenetics |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 |
_aExons _xgenetics |
| 650 | 0 | 4 |
_aFactor IX _xgenetics |
| 650 | 0 | 4 | _aGenetic Therapy |
| 650 | 0 | 4 |
_aGenetic Vectors _xadministration & dosage |
| 650 | 0 | 4 |
_aHemophilia A _xgenetics |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aInterferon-gamma _xmetabolism |
| 650 | 0 | 4 |
_aIntrons _xgenetics |
| 650 | 0 | 4 |
_aLiver _ximmunology |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 | _aMolecular Sequence Data |
| 650 | 0 | 4 |
_aMonocytes _xmetabolism |
| 650 | 0 | 4 | _aTransduction, Genetic |
| 700 | 1 | _aPierce, Glenn F | |
| 700 | 1 | _aArruda, Valder R | |
| 700 | 1 | _aGlader, Bertil | |
| 700 | 1 | _aRagni, Margaret | |
| 700 | 1 | _aRasko, John J | |
| 700 | 1 | _aRasko, John | |
| 700 | 1 | _aOzelo, Margareth C | |
| 700 | 1 | _aHoots, Keith | |
| 700 | 1 | _aBlatt, Philip | |
| 700 | 1 | _aKonkle, Barbara | |
| 700 | 1 | _aDake, Michael | |
| 700 | 1 | _aKaye, Robin | |
| 700 | 1 | _aRazavi, Mahmood | |
| 700 | 1 | _aZajko, Albert | |
| 700 | 1 | _aZehnder, James | |
| 700 | 1 | _aRustagi, Pradip K | |
| 700 | 1 | _aNakai, Hiroyuki | |
| 700 | 1 | _aChew, Amy | |
| 700 | 1 | _aLeonard, Debra | |
| 700 | 1 | _aWright, J Fraser | |
| 700 | 1 | _aLessard, Ruth R | |
| 700 | 1 | _aSommer, Jürg M | |
| 700 | 1 | _aTigges, Michael | |
| 700 | 1 | _aSabatino, Denise | |
| 700 | 1 | _aLuk, Alvin | |
| 700 | 1 | _aJiang, Haiyan | |
| 700 | 1 | _aMingozzi, Federico | |
| 700 | 1 | _aCouto, Linda | |
| 700 | 1 | _aErtl, Hildegund C | |
| 700 | 1 | _aHigh, Katherine A | |
| 700 | 1 | _aKay, Mark A | |
| 773 | 0 |
_tNature medicine _gvol. 12 _gno. 3 _gp. 342-7 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/nm1358 _zAvailable from publisher's website |
| 999 |
_c16086761 _d16086761 |
||