000 02411 a2200697 4500
005 20250515013201.0
264 0 _c20060613
008 200606s 0 0 eng d
022 _a0021-9258
024 7 _a10.1074/jbc.M508343200
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSalvatorelli, Emanuela
245 0 0 _aDefective one- or two-electron reduction of the anticancer anthracycline epirubicin in human heart. Relative importance of vesicular sequestration and impaired efficiency of electron addition.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cApr 2006
300 _a10990-1001 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAconitate Hydratase
_xmetabolism
650 0 4 _aAdenosine Triphosphatases
_xchemistry
650 0 4 _aAged
650 0 4 _aAntibiotics, Antineoplastic
_xpharmacology
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aArea Under Curve
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Membrane
_xmetabolism
650 0 4 _aCell-Free System
650 0 4 _aCells, Cultured
650 0 4 _aCytoplasm
_xmetabolism
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aElectrons
650 0 4 _aEpirubicin
_xchemistry
650 0 4 _aFemale
650 0 4 _aFluorescent Dyes
_xpharmacology
650 0 4 _aHumans
650 0 4 _aHydrogen Peroxide
_xchemistry
650 0 4 _aInhibitory Concentration 50
650 0 4 _aKinetics
650 0 4 _aMacrolides
_xchemistry
650 0 4 _aMale
650 0 4 _aMicroscopy, Confocal
650 0 4 _aMicroscopy, Fluorescence
650 0 4 _aMiddle Aged
650 0 4 _aMitochondria
_xmetabolism
650 0 4 _aModels, Chemical
650 0 4 _aMyocardium
_xmetabolism
650 0 4 _aOxidation-Reduction
650 0 4 _aOxygen
_xmetabolism
650 0 4 _aProtein Biosynthesis
650 0 4 _aProtons
650 0 4 _aReactive Oxygen Species
650 0 4 _aTime Factors
700 1 _aGuarnieri, Simone
700 1 _aMenna, Pierantonio
700 1 _aLiberi, Giovanni
700 1 _aCalafiore, Antonio M
700 1 _aMariggiò, Maria A
700 1 _aMordente, Alvaro
700 1 _aGianni, Luca
700 1 _aMinotti, Giorgio
773 0 _tThe Journal of biological chemistry
_gvol. 281
_gno. 16
_gp. 10990-1001
856 4 0 _uhttps://doi.org/10.1074/jbc.M508343200
_zAvailable from publisher's website
999 _c16039571
_d16039571