000 01985 a2200553 4500
005 20250515012906.0
264 0 _c20060208
008 200602s 0 0 eng d
022 _a0009-9236
024 7 _a10.1016/j.clpt.2005.10.003
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLeitner, Judith M
245 0 0 _aRecombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia.
_h[electronic resource]
260 _bClinical pharmacology and therapeutics
_cJan 2006
300 _a23-34 p.
_bdigital
500 _aPublication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
650 0 4 _aAdult
650 0 4 _aAnticoagulants
650 0 4 _aAntithrombins
_xpharmacokinetics
650 0 4 _aBiomarkers
650 0 4 _aBlood Coagulation
_xdrug effects
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDouble-Blind Method
650 0 4 _aEndotoxemia
_xchemically induced
650 0 4 _aFibrinolysis
_xdrug effects
650 0 4 _aHemodynamics
_xdrug effects
650 0 4 _aHumans
650 0 4 _aIn Vitro Techniques
650 0 4 _aInflammation Mediators
_xblood
650 0 4 _aInterleukin-6
_xmetabolism
650 0 4 _aLeukocyte Count
650 0 4 _aLipopolysaccharides
_xpharmacology
650 0 4 _aMale
650 0 4 _aPartial Thromboplastin Time
650 0 4 _aPeptide Fragments
_xanalysis
650 0 4 _aProthrombin
_xanalysis
650 0 4 _aProthrombin Time
650 0 4 _aRNA, Messenger
_xbiosynthesis
650 0 4 _aRecombinant Proteins
_xpharmacokinetics
650 0 4 _aThrombelastography
650 0 4 _aThrombin
_xbiosynthesis
700 1 _aFirbas, Christa
700 1 _aMayr, Florian B
700 1 _aReiter, Rosemarie A
700 1 _aSteinlechner, Barbara
700 1 _aJilma, Bernd
773 0 _tClinical pharmacology and therapeutics
_gvol. 79
_gno. 1
_gp. 23-34
856 4 0 _uhttps://doi.org/10.1016/j.clpt.2005.10.003
_zAvailable from publisher's website
999 _c16029692
_d16029692