000 01819 a2200445 4500
005 20250515010738.0
264 0 _c20060413
008 200604s 0 0 eng d
022 _a0022-3565
024 7 _a10.1124/jpet.105.091587
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSteckelbroeck, Stephan
245 0 0 _aTibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.
_h[electronic resource]
260 _bThe Journal of pharmacology and experimental therapeutics
_cMar 2006
300 _a1300-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _a17-Hydroxysteroid Dehydrogenases
_xphysiology
650 0 4 _a20-Hydroxysteroid Dehydrogenases
_xphysiology
650 0 4 _a3-Hydroxysteroid Dehydrogenases
_xphysiology
650 0 4 _aAldo-Keto Reductase Family 1 Member C3
650 0 4 _aBile Acids and Salts
_xpharmacology
650 0 4 _aCatalysis
650 0 4 _aCells, Cultured
650 0 4 _aFlufenamic Acid
_xpharmacology
650 0 4 _aHepatocytes
_xenzymology
650 0 4 _aHumans
650 0 4 _aHydroxyprostaglandin Dehydrogenases
_xphysiology
650 0 4 _aHydroxysteroid Dehydrogenases
_xphysiology
650 0 4 _aLiver
_xmetabolism
650 0 4 _aNorpregnenes
_xmetabolism
650 0 4 _aOxidoreductases
_xphysiology
650 0 4 _aPhenolphthalein
_xpharmacology
700 1 _aOyesanmi, Busola
700 1 _aJin, Yi
700 1 _aLee, Seon-Hwa
700 1 _aKloosterboer, Helenius J
700 1 _aPenning, Trevor M
773 0 _tThe Journal of pharmacology and experimental therapeutics
_gvol. 316
_gno. 3
_gp. 1300-9
856 4 0 _uhttps://doi.org/10.1124/jpet.105.091587
_zAvailable from publisher's website
999 _c15960485
_d15960485