000			02216 a2200709 4500
005			20250515010610.0
264		0	_c20060207
008			200602s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm050522v _2doi
040			_aNLM _beng _cNLM
100	1		_aNapper, Andrew D
245	0	0	_aDiscovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. _h[electronic resource]
260			_bJournal of medicinal chemistry _cDec 2005
300			_a8045-54 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aBiological Availability
650	0	4	_aCHO Cells
650	0	4	_aCarbazoles _xchemical synthesis
650	0	4	_aCell Membrane Permeability
650	0	4	_aCricetinae
650	0	4	_aCricetulus
650	0	4	_aDrug Stability
650	0	4	_aFluorometry
650	0	4	_aHistone Deacetylase Inhibitors
650	0	4	_aHistone Deacetylases _xchemistry
650	0	4	_aHumans
650	0	4	_aIn Vitro Techniques
650	0	4	_aIndoles _xchemical synthesis
650	0	4	_aKinetics
650	0	4	_aMice
650	0	4	_aMice, Inbred C57BL
650	0	4	_aMicrosomes, Liver _xmetabolism
650	0	4	_aNAD _xchemistry
650	0	4	_aNAD+ Nucleosidase _xchemistry
650	0	4	_aNiacinamide _xchemistry
650	0	4	_aRats
650	0	4	_aRecombinant Proteins _xantagonists & inhibitors
650	0	4	_aSirtuin 1
650	0	4	_aSirtuins _xantagonists & inhibitors
650	0	4	_aStereoisomerism
650	0	4	_aStructure-Activity Relationship
700	1		_aHixon, Jeffrey
700	1		_aMcDonagh, Thomas
700	1		_aKeavey, Kenneth
700	1		_aPons, Jean-Francois
700	1		_aBarker, Jonathan
700	1		_aYau, Wei Tsung
700	1		_aAmouzegh, Patricia
700	1		_aFlegg, Adam
700	1		_aHamelin, Estelle
700	1		_aThomas, Russell J
700	1		_aKates, Michael
700	1		_aJones, Stephen
700	1		_aNavia, Manuel A
700	1		_aSaunders, Jeffrey O
700	1		_aDiStefano, Peter S
700	1		_aCurtis, Rory
773	0		_tJournal of medicinal chemistry _gvol. 48 _gno. 25 _gp. 8045-54
856	4	0	_uhttps://doi.org/10.1021/jm050522v _zAvailable from publisher's website
999			_c15957214 _d15957214