000 01867 a2200529 4500
005 20250515005634.0
264 0 _c20060427
008 200604s 0 0 eng d
022 _a0960-894X
024 7 _a10.1016/j.bmcl.2005.11.012
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJones, Philip
245 0 0 _aPharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA(A) alpha5 inverse agonist for cognitive dysfunction.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cFeb 2006
300 _a872-5 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAnimals
650 0 4 _aDogs
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aGABA Agonists
_xchemical synthesis
650 0 4 _aGABA-A Receptor Agonists
650 0 4 _aHydrolysis
650 0 4 _aIsoxazoles
_xchemical synthesis
650 0 4 _aMacaca mulatta
650 0 4 _aMice
650 0 4 _aMolecular Conformation
650 0 4 _aProtein Subunits
_xagonists
650 0 4 _aRats
650 0 4 _aStereoisomerism
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTissue Distribution
650 0 4 _aTriazines
_xchemical synthesis
700 1 _aAtack, John R
700 1 _aBraun, Matthew P
700 1 _aCato, Brian P
700 1 _aChambers, Mark S
700 1 _aO'Connor, Desmond
700 1 _aCook, Susan M
700 1 _aHobbs, Sarah C
700 1 _aMaxey, Robert
700 1 _aSzekeres, Helen J
700 1 _aSzeto, Nicola
700 1 _aWafford, Keith A
700 1 _aMacLeod, Angus M
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 16
_gno. 4
_gp. 872-5
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2005.11.012
_zAvailable from publisher's website
999 _c15926745
_d15926745