| 000 | 01586 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250515005626.0 | ||
| 264 | 0 | _c20060209 | |
| 008 | 200602s 0 0 eng d | ||
| 022 | _a0022-2623 | ||
| 024 | 7 |
_a10.1021/jm050631+ _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aVidal, Paloma | |
| 245 | 0 | 0 |
_aPreorganization of the hydroxyethylene dipeptide isostere: the preferred conformation in solution resembles the conformation bound to BACE. _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cDec 2005 |
||
| 300 |
_a7623-7 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAmyloid Precursor Protein Secretases |
| 650 | 0 | 4 | _aAspartic Acid Endopeptidases |
| 650 | 0 | 4 | _aCrystallography, X-Ray |
| 650 | 0 | 4 |
_aDipeptides _xchemistry |
| 650 | 0 | 4 |
_aEndopeptidases _xchemistry |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLeucine _xchemistry |
| 650 | 0 | 4 | _aMagnetic Resonance Spectroscopy |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aMolecular Conformation |
| 650 | 0 | 4 |
_aPhenylalanine _xchemistry |
| 650 | 0 | 4 |
_aProtease Inhibitors _xchemistry |
| 650 | 0 | 4 | _aSolutions |
| 650 | 0 | 4 |
_aValine _xchemistry |
| 700 | 1 | _aTimm, David | |
| 700 | 1 | _aBroughton, Howard | |
| 700 | 1 | _aChen, Shu-Hui | |
| 700 | 1 | _aMartín, José A | |
| 700 | 1 | _aRivera-Sagredo, Alfonso | |
| 700 | 1 | _aMcCarthy, James R | |
| 700 | 1 | _aShapiro, Michael J | |
| 700 | 1 | _aEspinosa, Juan F | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 48 _gno. 24 _gp. 7623-7 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/jm050631+ _zAvailable from publisher's website |
| 999 |
_c15926262 _d15926262 |
||