| 000 | 01619 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250515004050.0 | ||
| 264 | 0 | _c20060321 | |
| 008 | 200603s 0 0 eng d | ||
| 022 | _a0960-894X | ||
| 024 | 7 |
_a10.1016/j.bmcl.2005.09.003 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRojo, Isabel | |
| 245 | 0 | 0 |
_aMacrocyclic peptidomimetic inhibitors of beta-secretase (BACE): first X-ray structure of a macrocyclic peptidomimetic-BACE complex. _h[electronic resource] |
| 260 |
_bBioorganic & medicinal chemistry letters _cJan 2006 |
||
| 300 |
_a191-5 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 |
_aAlzheimer Disease _xdrug therapy |
| 650 | 0 | 4 | _aAmyloid Precursor Protein Secretases |
| 650 | 0 | 4 |
_aAmyloid beta-Protein Precursor _xchemistry |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aAspartic Acid Endopeptidases |
| 650 | 0 | 4 | _aCell Line |
| 650 | 0 | 4 |
_aChemistry, Pharmaceutical _xmethods |
| 650 | 0 | 4 |
_aCrystallography, X-Ray _xmethods |
| 650 | 0 | 4 | _aDrug Design |
| 650 | 0 | 4 |
_aEndopeptidases _xchemistry |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aKinetics |
| 650 | 0 | 4 | _aModels, Chemical |
| 650 | 0 | 4 | _aModels, Molecular |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aProtein Structure, Tertiary |
| 700 | 1 | _aMartín, José Alfredo | |
| 700 | 1 | _aBroughton, Howard | |
| 700 | 1 | _aTimm, David | |
| 700 | 1 | _aErickson, Jon | |
| 700 | 1 | _aYang, Hsiu-Chiung | |
| 700 | 1 | _aMcCarthy, James R | |
| 773 | 0 |
_tBioorganic & medicinal chemistry letters _gvol. 16 _gno. 1 _gp. 191-5 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmcl.2005.09.003 _zAvailable from publisher's website |
| 999 |
_c15876565 _d15876565 |
||