| 000 | 02676 a2200769 4500 | ||
|---|---|---|---|
| 005 | 20250515002132.0 | ||
| 264 | 0 | _c20060331 | |
| 008 | 200603s 0 0 eng d | ||
| 022 | _a0022-3565 | ||
| 024 | 7 |
_a10.1124/jpet.105.089920 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aAtack, John R | |
| 245 | 0 | 0 |
_aTPA023 [7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an agonist selective for alpha2- and alpha3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates. _h[electronic resource] |
| 260 |
_bThe Journal of pharmacology and experimental therapeutics _cJan 2006 |
||
| 300 |
_a410-22 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAcoustic Stimulation |
| 650 | 0 | 4 | _aAdrenergic alpha-1 Receptor Antagonists |
| 650 | 0 | 4 |
_aAdrenergic alpha-Agonists _xpharmacology |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aAnti-Anxiety Agents |
| 650 | 0 | 4 |
_aAnticonvulsants _xpharmacology |
| 650 | 0 | 4 | _aAutoradiography |
| 650 | 0 | 4 |
_aConditioning, Operant _xdrug effects |
| 650 | 0 | 4 |
_aConvulsants _xpharmacology |
| 650 | 0 | 4 |
_aDrinking _xdrug effects |
| 650 | 0 | 4 |
_aEmotions _xdrug effects |
| 650 | 0 | 4 |
_aFear _xdrug effects |
| 650 | 0 | 4 |
_aFlumazenil _xmetabolism |
| 650 | 0 | 4 |
_aGABA Modulators _xmetabolism |
| 650 | 0 | 4 | _aGABA-A Receptor Agonists |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 |
_aPentylenetetrazole _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPostural Balance _xdrug effects |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 |
_aPyridazines _xpharmacology |
| 650 | 0 | 4 | _aRadioligand Assay |
| 650 | 0 | 4 | _aRats |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 | _aReceptors, GABA-A |
| 650 | 0 | 4 |
_aRecombinant Proteins _xmetabolism |
| 650 | 0 | 4 |
_aReflex, Startle _xdrug effects |
| 650 | 0 | 4 | _aSaimiri |
| 650 | 0 | 4 |
_aSubstance Withdrawal Syndrome _xpsychology |
| 650 | 0 | 4 |
_aTriazoles _xpharmacology |
| 700 | 1 | _aWafford, Keith A | |
| 700 | 1 | _aTye, Spencer J | |
| 700 | 1 | _aCook, Susan M | |
| 700 | 1 | _aSohal, Bindi | |
| 700 | 1 | _aPike, Andrew | |
| 700 | 1 | _aSur, Cyrille | |
| 700 | 1 | _aMelillo, David | |
| 700 | 1 | _aBristow, Linda | |
| 700 | 1 | _aBromidge, Fran | |
| 700 | 1 | _aRagan, Ian | |
| 700 | 1 | _aKerby, Julie | |
| 700 | 1 | _aStreet, Les | |
| 700 | 1 | _aCarling, Robert | |
| 700 | 1 | _aCastro, José L | |
| 700 | 1 | _aWhiting, Paul | |
| 700 | 1 | _aDawson, Gerard R | |
| 700 | 1 | _aMcKernan, Ruth M | |
| 773 | 0 |
_tThe Journal of pharmacology and experimental therapeutics _gvol. 316 _gno. 1 _gp. 410-22 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/jpet.105.089920 _zAvailable from publisher's website |
| 999 |
_c15815354 _d15815354 |
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