000			02238 a2200613 4500
005			20250515001713.0
264		0	_c20060216
008			200602s 0 0 eng d
022			_a0950-9232
024	7		_a10.1038/sj.onc.1209049 _2doi
040			_aNLM _beng _cNLM
100	1		_aOta, H
245	0	0	_aSirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells. _h[electronic resource]
260			_bOncogene _cJan 2006
300			_a176-85 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650	0	4	_aBenzamides _xpharmacology
650	0	4	_aBreast Neoplasms _xdrug therapy
650	0	4	_aCellular Senescence _xdrug effects
650	0	4	_aEnzyme Activation _xdrug effects
650	0	4	_aEpidermal Growth Factor _xpharmacology
650	0	4	_aErbB Receptors _xmetabolism
650	0	4	_aGenes, ras _xphysiology
650	0	4	_aHistone Deacetylase Inhibitors
650	0	4	_aHumans
650	0	4	_aInsulin-Like Growth Factor I _xpharmacology
650	0	4	_aLung Neoplasms _xdrug therapy
650	0	4	_aMitogen-Activated Protein Kinase 1 _xmetabolism
650	0	4	_aMitogen-Activated Protein Kinase 3 _xmetabolism
650	0	4	_aNaphthols _xpharmacology
650	0	4	_aPhosphatidylinositol 3-Kinases _xmetabolism
650	0	4	_aPhosphorylation _xdrug effects
650	0	4	_aPlasminogen Activator Inhibitor 1 _xmetabolism
650	0	4	_aProto-Oncogene Proteins c-akt _xmetabolism
650	0	4	_aReceptor, IGF Type 1 _xmetabolism
650	0	4	_aSignal Transduction _xdrug effects
650	0	4	_aSirtuin 1
650	0	4	_aSirtuins _xantagonists & inhibitors
650	0	4	_aTumor Cells, Cultured
650	0	4	_aTyrosine _xmetabolism
650	0	4	_abeta-Galactosidase _xmetabolism
650	0	4	_ap38 Mitogen-Activated Protein Kinases _xmetabolism
700	1		_aTokunaga, E
700	1		_aChang, K
700	1		_aHikasa, M
700	1		_aIijima, K
700	1		_aEto, M
700	1		_aKozaki, K
700	1		_aAkishita, M
700	1		_aOuchi, Y
700	1		_aKaneki, M
773	0		_tOncogene _gvol. 25 _gno. 2 _gp. 176-85
856	4	0	_uhttps://doi.org/10.1038/sj.onc.1209049 _zAvailable from publisher's website
999			_c15802674 _d15802674