000 02232 a2200577 4500
005 20250515001424.0
264 0 _c20060207
008 200602s 0 0 eng d
022 _a0006-4971
024 7 _a10.1182/blood-2005-07-2743
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aStark, Michal
245 0 0 _aLoss of Sp1 function via inhibitory phosphorylation in antifolate-resistant human leukemia cells with down-regulation of the reduced folate carrier.
_h[electronic resource]
260 _bBlood
_cJan 2006
300 _a708-15 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _a1-Methyl-3-isobutylxanthine
_xpharmacology
650 0 4 _aAlkaline Phosphatase
_xmetabolism
650 0 4 _aBinding Sites
650 0 4 _aCyclic AMP
_xmetabolism
650 0 4 _aCyclic AMP-Dependent Protein Kinases
_xmetabolism
650 0 4 _aCyclic GMP
_xanalogs & derivatives
650 0 4 _aDown-Regulation
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aElectrophoretic Mobility Shift Assay
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFolic Acid Antagonists
_xpharmacology
650 0 4 _aGC Rich Sequence
650 0 4 _aHumans
650 0 4 _aLeukemia, T-Cell
_xdrug therapy
650 0 4 _aLuciferases
_xmetabolism
650 0 4 _aMembrane Transport Proteins
_xgenetics
650 0 4 _aNuclear Proteins
650 0 4 _aOkadaic Acid
_xpharmacology
650 0 4 _aPhosphodiesterase Inhibitors
_xpharmacology
650 0 4 _aPhosphoprotein Phosphatases
_xantagonists & inhibitors
650 0 4 _aPhosphorylation
650 0 4 _aPlatelet Aggregation Inhibitors
_xpharmacology
650 0 4 _aPromoter Regions, Genetic
_xgenetics
650 0 4 _aProtein Phosphatase 2
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aReduced Folate Carrier Protein
650 0 4 _aSp1 Transcription Factor
_xmetabolism
650 0 4 _aThionucleotides
_xpharmacology
650 0 4 _aTranscription, Genetic
650 0 4 _aTransfection
650 0 4 _aTumor Cells, Cultured
700 1 _aAssaraf, Yehuda G
773 0 _tBlood
_gvol. 107
_gno. 2
_gp. 708-15
856 4 0 _uhttps://doi.org/10.1182/blood-2005-07-2743
_zAvailable from publisher's website
999 _c15793366
_d15793366