000 02609 a2200685 4500
005 20250514233308.0
264 0 _c20051223
008 200512s 0 0 eng d
022 _a1019-6439
040 _aNLM
_beng
_cNLM
100 1 _aCoudray, Anne-Marie
245 0 0 _aIncreased anticancer activity of the thymidylate synthase inhibitor BGC9331 combined with the topoisomerase I inhibitor SN-38 in human colorectal and breast cancer cells: induction of apoptosis and ROCK cleavage through caspase-3-dependent and -independent mechanisms.
_h[electronic resource]
260 _bInternational journal of oncology
_cAug 2005
300 _a553-61 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBreast Neoplasms
_xmetabolism
650 0 4 _aCamptothecin
_xanalogs & derivatives
650 0 4 _aCaspase 3
650 0 4 _aCaspase Inhibitors
650 0 4 _aCaspases
_xmetabolism
650 0 4 _aCell Cycle
_xdrug effects
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aColorectal Neoplasms
_xmetabolism
650 0 4 _aCysteine Proteinase Inhibitors
_xpharmacology
650 0 4 _aDNA Topoisomerases, Type I
_xmetabolism
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Synergism
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aFluorouracil
_xpharmacology
650 0 4 _aFolic Acid Antagonists
_xpharmacology
650 0 4 _aGlutamates
_xpharmacology
650 0 4 _aGuanine
_xanalogs & derivatives
650 0 4 _aHT29 Cells
650 0 4 _aHumans
650 0 4 _aIntracellular Signaling Peptides and Proteins
650 0 4 _aIrinotecan
650 0 4 _aOligopeptides
_xpharmacology
650 0 4 _aOrganoplatinum Compounds
_xpharmacology
650 0 4 _aOxaliplatin
650 0 4 _aPemetrexed
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aQuinazolines
_xpharmacology
650 0 4 _aThymidylate Synthase
_xantagonists & inhibitors
650 0 4 _aTime Factors
650 0 4 _aTopoisomerase I Inhibitors
650 0 4 _arho-Associated Kinases
700 1 _aLouvet, Christophe
700 1 _aKornprobst, Michel
700 1 _aRaymond, Eric
700 1 _aAndré, Thierry
700 1 _aTournigand, Christophe
700 1 _aFaivre, Sandrine
700 1 _aDe Gramont, Aimery
700 1 _aLarsen, Annette K
700 1 _aGespach, Christian
773 0 _tInternational journal of oncology
_gvol. 27
_gno. 2
_gp. 553-61
999 _c15666402
_d15666402