000			02024 a2200625 4500
005			20250514232230.0
264		0	_c20050823
008			200508s 0 0 eng d
022			_a0022-2623
024	7		_a10.1021/jm0502135 _2doi
040			_aNLM _beng _cNLM
100	1		_aShi, Guo Q
245	0	0	_aDesign and synthesis of alpha-aryloxyphenylacetic acid derivatives: a novel class of PPARalpha/gamma dual agonists with potent antihyperglycemic and lipid modulating activity. _h[electronic resource]
260			_bJournal of medicinal chemistry _cJun 2005
300			_a4457-68 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAnimals
650	0	4	_aCricetinae
650	0	4	_aCrystallography, X-Ray
650	0	4	_aDiabetes Mellitus, Type 2 _xdrug therapy
650	0	4	_aDogs
650	0	4	_aHypoglycemic Agents _xchemical synthesis
650	0	4	_aHypolipidemic Agents _xchemical synthesis
650	0	4	_aKinetics
650	0	4	_aMale
650	0	4	_aMesocricetus
650	0	4	_aMice
650	0	4	_aMice, Inbred C57BL
650	0	4	_aModels, Animal
650	0	4	_aModels, Molecular
650	0	4	_aMolecular Structure
650	0	4	_aPPAR alpha _xagonists
650	0	4	_aPPAR delta _xagonists
650	0	4	_aPhenylacetates _xchemical synthesis
650	0	4	_aRats
650	0	4	_aRats, Sprague-Dawley
650	0	4	_aStructure-Activity Relationship
700	1		_aDropinski, James F
700	1		_aMcKeever, Brian M
700	1		_aXu, Shihua
700	1		_aBecker, Joseph W
700	1		_aBerger, Joel P
700	1		_aMacNaul, Karen L
700	1		_aElbrecht, Alex
700	1		_aZhou, Gaochao
700	1		_aDoebber, Thomas W
700	1		_aWang, Peiran
700	1		_aChao, Yu-Sheng
700	1		_aForrest, Mike
700	1		_aHeck, James V
700	1		_aMoller, David E
700	1		_aJones, A Brian
773	0		_tJournal of medicinal chemistry _gvol. 48 _gno. 13 _gp. 4457-68
856	4	0	_uhttps://doi.org/10.1021/jm0502135 _zAvailable from publisher's website
999			_c15632516 _d15632516