000 02268 a2200601 4500
005 20250514232146.0
264 0 _c20060818
008 200608s 0 0 eng d
022 _a1540-658X
024 7 _a10.1089/adt.2005.3.273
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHardcastle, Anthea
245 0 0 _aSolid-phase immunoassays in mechanism-based drug discovery: their application in the development of inhibitors of the molecular chaperone heat-shock protein 90.
_h[electronic resource]
260 _bAssay and drug development technologies
_cJun 2005
300 _a273-85 p.
_bdigital
500 _aPublication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBenzoquinones
650 0 4 _aBlotting, Western
650 0 4 _aCarrier Proteins
_xantagonists & inhibitors
650 0 4 _aCell Extracts
_xanalysis
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Design
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aHCT116 Cells
650 0 4 _aHSP70 Heat-Shock Proteins
_xantagonists & inhibitors
650 0 4 _aHSP90 Heat-Shock Proteins
_xantagonists & inhibitors
650 0 4 _aHT29 Cells
650 0 4 _aHeterocyclic Compounds, 2-Ring
_xpharmacology
650 0 4 _aHumans
650 0 4 _aImmunoassay
_xmethods
650 0 4 _aIntracellular Signaling Peptides and Proteins
650 0 4 _aLactams, Macrocyclic
650 0 4 _aLymphocytes
_xchemistry
650 0 4 _aMice
650 0 4 _aNeoplasm Transplantation
650 0 4 _aProto-Oncogene Proteins c-raf
_xantagonists & inhibitors
650 0 4 _aPyrazoles
_xpharmacology
650 0 4 _aQuinones
_xpharmacology
650 0 4 _aRifabutin
_xanalogs & derivatives
650 0 4 _aTechnology, Pharmaceutical
_xmethods
650 0 4 _aTransplantation, Heterologous
650 0 4 _aeIF-2 Kinase
_xantagonists & inhibitors
700 1 _aBoxall, Kathy
700 1 _aRichards, Juliet
700 1 _aTomlin, Peter
700 1 _aSharp, Swee
700 1 _aClarke, Paul
700 1 _aWorkman, Paul
700 1 _aAherne, Wynne
773 0 _tAssay and drug development technologies
_gvol. 3
_gno. 3
_gp. 273-85
856 4 0 _uhttps://doi.org/10.1089/adt.2005.3.273
_zAvailable from publisher's website
999 _c15630109
_d15630109