000 02731 a2200769 4500
005 20250514231508.0
264 0 _c20050906
008 200509s 0 0 eng d
022 _a1535-6108
024 7 _a10.1016/j.ccr.2005.05.014
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSamuels, Yardena
245 0 0 _aMutant PIK3CA promotes cell growth and invasion of human cancer cells.
_h[electronic resource]
260 _bCancer cell
_cJun 2005
300 _a561-73 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
650 0 4 _aAmino Acid Substitution
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xgenetics
650 0 4 _aApoptosis Regulatory Proteins
650 0 4 _aBase Sequence
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Movement
_xgenetics
650 0 4 _aCell Proliferation
650 0 4 _aChromones
_xpharmacology
650 0 4 _aClass I Phosphatidylinositol 3-Kinases
650 0 4 _aDNA-Binding Proteins
_xgenetics
650 0 4 _aEnzyme Inhibitors
_xpharmacology
650 0 4 _aForkhead Box Protein O1
650 0 4 _aForkhead Box Protein O3
650 0 4 _aForkhead Transcription Factors
650 0 4 _aGene Targeting
650 0 4 _aGrowth Substances
_xdeficiency
650 0 4 _aHumans
650 0 4 _aInsulin
_xdeficiency
650 0 4 _aMembrane Glycoproteins
_xphysiology
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMorpholines
_xpharmacology
650 0 4 _aMutation
650 0 4 _aNeoplasm Invasiveness
_xgenetics
650 0 4 _aNeoplasms, Experimental
_xgenetics
650 0 4 _aPhosphatidylinositol 3-Kinases
_xgenetics
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Serine-Threonine Kinases
_xgenetics
650 0 4 _aProto-Oncogene Proteins
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTNF-Related Apoptosis-Inducing Ligand
650 0 4 _aTranscription Factors
_xgenetics
650 0 4 _aTumor Necrosis Factor-alpha
_xphysiology
650 0 4 _aXenograft Model Antitumor Assays
_xmethods
700 1 _aDiaz, Luis A
700 1 _aSchmidt-Kittler, Oleg
700 1 _aCummins, Jordan M
700 1 _aDelong, Laura
700 1 _aCheong, Ian
700 1 _aRago, Carlo
700 1 _aHuso, David L
700 1 _aLengauer, Christoph
700 1 _aKinzler, Kenneth W
700 1 _aVogelstein, Bert
700 1 _aVelculescu, Victor E
773 0 _tCancer cell
_gvol. 7
_gno. 6
_gp. 561-73
856 4 0 _uhttps://doi.org/10.1016/j.ccr.2005.05.014
_zAvailable from publisher's website
999 _c15610400
_d15610400