000			02079 a2200577 4500
005			20250514223917.0
264		0	_c20051209
008			200512s 0 0 eng d
022			_a1478-6362
024	7		_a10.1186/ar1688 _2doi
040			_aNLM _beng _cNLM
100	1		_aRuderman, Eric M
245	0	0	_aThe evolving clinical profile of abatacept (CTLA4-Ig): a novel co-stimulatory modulator for the treatment of rheumatoid arthritis. _h[electronic resource]
260			_bArthritis research & therapy _c2005
300			_aS21-5 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
650	0	4	_aAbatacept
650	0	4	_aAnimals
650	0	4	_aAntigen Presentation
650	0	4	_aAntigens, CD
650	0	4	_aAntigens, Differentiation _xgenetics
650	0	4	_aAntirheumatic Agents _xpharmacology
650	0	4	_aArthritis, Experimental _xdrug therapy
650	0	4	_aArthritis, Rheumatoid _xdrug therapy
650	0	4	_aAutoimmune Diseases _xdrug therapy
650	0	4	_aB7-1 Antigen _ximmunology
650	0	4	_aB7-2 Antigen _ximmunology
650	0	4	_aCD28 Antigens _ximmunology
650	0	4	_aCTLA-4 Antigen
650	0	4	_aClinical Trials, Phase II as Topic
650	0	4	_aClinical Trials, Phase III as Topic
650	0	4	_aDouble-Blind Method
650	0	4	_aDrug Evaluation, Preclinical
650	0	4	_aFemale
650	0	4	_aHumans
650	0	4	_aImmunoconjugates _xpharmacology
650	0	4	_aImmunoglobulin Fc Fragments _xgenetics
650	0	4	_aLymphocyte Activation _xdrug effects
650	0	4	_aMale
650	0	4	_aMice
650	0	4	_aMiddle Aged
650	0	4	_aMulticenter Studies as Topic
650	0	4	_aPilot Projects
650	0	4	_aProtein Structure, Tertiary
650	0	4	_aReceptors, Antigen, T-Cell _ximmunology
650	0	4	_aRecombinant Fusion Proteins _xtherapeutic use
650	0	4	_aTreatment Outcome
700	1		_aPope, Richard M
773	0		_tArthritis research & therapy _gvol. 7 Suppl 2 _gp. S21-5
856	4	0	_uhttps://doi.org/10.1186/ar1688 _zAvailable from publisher's website
999			_c15501580 _d15501580