000 02507 a2200685 4500
005 20250514223434.0
264 0 _c20050802
008 200508s 0 0 eng d
022 _a0021-9258
024 7 _a10.1074/jbc.M500540200
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKim, Su-Jin
245 0 0 _aGlucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cJun 2005
300 _a22297-307 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aApoptosis
650 0 4 _aBlotting, Western
650 0 4 _aCell Line
650 0 4 _aCell Survival
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDown-Regulation
650 0 4 _aForkhead Box Protein O1
650 0 4 _aForkhead Transcription Factors
650 0 4 _aGastric Inhibitory Polypeptide
_xchemistry
650 0 4 _aHumans
650 0 4 _aImmunohistochemistry
650 0 4 _aIslets of Langerhans
_xcytology
650 0 4 _aLuciferases
_xmetabolism
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aMice, Knockout
650 0 4 _aMice, Transgenic
650 0 4 _aMicroscopy, Confocal
650 0 4 _aMicroscopy, Fluorescence
650 0 4 _aPhosphatidylinositol 3-Kinases
_xmetabolism
650 0 4 _aPhosphorylation
650 0 4 _aPromoter Regions, Genetic
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
_xmetabolism
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xmetabolism
650 0 4 _aRats
650 0 4 _aRats, Zucker
650 0 4 _aSignal Transduction
650 0 4 _aSubcellular Fractions
650 0 4 _aTime Factors
650 0 4 _aTranscription Factors
_xmetabolism
650 0 4 _aTranscription, Genetic
650 0 4 _abcl-2-Associated X Protein
700 1 _aWinter, Kyle
700 1 _aNian, Cuilan
700 1 _aTsuneoka, Makoto
700 1 _aKoda, Yoshiro
700 1 _aMcIntosh, Christopher H S
773 0 _tThe Journal of biological chemistry
_gvol. 280
_gno. 23
_gp. 22297-307
856 4 0 _uhttps://doi.org/10.1074/jbc.M500540200
_zAvailable from publisher's website
999 _c15486772
_d15486772