000 | 02282 a2200625 4500 | ||
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005 | 20250514222808.0 | ||
264 | 0 | _c20050712 | |
008 | 200507s 0 0 eng d | ||
022 | _a0021-9258 | ||
024 | 7 |
_a10.1074/jbc.M501269200 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aThomas, James L | |
245 | 0 | 0 |
_aIdentification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2. _h[electronic resource] |
260 |
_bThe Journal of biological chemistry _cJun 2005 |
||
300 |
_a21321-8 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S. | ||
650 | 0 | 4 |
_a3-Hydroxysteroid Dehydrogenases _xchemistry |
650 | 0 | 4 | _aAllosteric Site |
650 | 0 | 4 | _aAmino Acid Sequence |
650 | 0 | 4 |
_aAndrostenols _xchemistry |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aArginine _xchemistry |
650 | 0 | 4 |
_aBaculoviridae _xmetabolism |
650 | 0 | 4 | _aBlotting, Western |
650 | 0 | 4 | _aCatalysis |
650 | 0 | 4 | _aCatalytic Domain |
650 | 0 | 4 | _aCell Line |
650 | 0 | 4 |
_aDNA Primers _xchemistry |
650 | 0 | 4 |
_aDihydrotestosterone _xanalogs & derivatives |
650 | 0 | 4 | _aDose-Response Relationship, Drug |
650 | 0 | 4 | _aElectrophoresis, Polyacrylamide Gel |
650 | 0 | 4 |
_aGlutamine _xchemistry |
650 | 0 | 4 |
_aHistidine _xchemistry |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aInsecta |
650 | 0 | 4 | _aKinetics |
650 | 0 | 4 | _aModels, Chemical |
650 | 0 | 4 | _aModels, Molecular |
650 | 0 | 4 | _aMolecular Sequence Data |
650 | 0 | 4 | _aMutagenesis, Site-Directed |
650 | 0 | 4 | _aMutation |
650 | 0 | 4 |
_aNAD _xchemistry |
650 | 0 | 4 | _aProtein Binding |
650 | 0 | 4 | _aProtein Conformation |
650 | 0 | 4 | _aSequence Homology, Amino Acid |
650 | 0 | 4 | _aStructure-Activity Relationship |
650 | 0 | 4 | _aSubstrate Specificity |
650 | 0 | 4 | _aTissue Distribution |
700 | 1 | _aBoswell, Elizabeth L | |
700 | 1 | _aScaccia, Launa A | |
700 | 1 | _aPletnev, Vladimir | |
700 | 1 | _aUmland, Timothy C | |
773 | 0 |
_tThe Journal of biological chemistry _gvol. 280 _gno. 22 _gp. 21321-8 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1074/jbc.M501269200 _zAvailable from publisher's website |
999 |
_c15468446 _d15468446 |