000 01857 a2200529 4500
005 20250514222758.0
264 0 _c20050516
008 200505s 0 0 eng d
022 _a0092-8674
024 7 _a10.1016/j.cell.2004.12.040
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBeuvink, Iwan
245 0 0 _aThe mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.
_h[electronic resource]
260 _bCell
_cMar 2005
300 _a747-59 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCell Cycle Proteins
_xantagonists & inhibitors
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCisplatin
_xpharmacology
650 0 4 _aCyclin-Dependent Kinase Inhibitor p21
650 0 4 _aDNA Damage
_xdrug effects
650 0 4 _aDrug Synergism
650 0 4 _aEverolimus
650 0 4 _aHumans
650 0 4 _aMutation
650 0 4 _aPolyribosomes
_xdrug effects
650 0 4 _aProtein Biosynthesis
_xdrug effects
650 0 4 _aProtein Kinases
_xgenetics
650 0 4 _aRNA, Small Interfering
_xgenetics
650 0 4 _aSirolimus
_xanalogs & derivatives
650 0 4 _aTOR Serine-Threonine Kinases
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aBoulay, Anne
700 1 _aFumagalli, Stefano
700 1 _aZilbermann, Frederic
700 1 _aRuetz, Stephan
700 1 _aO'Reilly, Terence
700 1 _aNatt, Francois
700 1 _aHall, Jonathan
700 1 _aLane, Heidi A
700 1 _aThomas, George
773 0 _tCell
_gvol. 120
_gno. 6
_gp. 747-59
856 4 0 _uhttps://doi.org/10.1016/j.cell.2004.12.040
_zAvailable from publisher's website
999 _c15467973
_d15467973